A Review on Synthesis of Quinoline Analogs as Antimalarial, Antibacterial and Anticancer agents

Numerous natural products possessing quinoline moiety exhibit interesting biological and pharmacological properties, such as antimalarial, antibacterial, antiasthmatic, antihypertensive, anti-inflammatory, immunosuppressive, antileishmanial, and anticancer  activity. Surprising, quinoline scaffold h...

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Main Authors: Ayana Melaku Yadessa, Digafie Zeleke
Format: Article
Language:English
Published: Adama Science and Technology University 2021-06-01
Series:Ethiopian Journal of Science and Sustainable Development
Online Access:https://ejssd.astu.edu.et/index.php/EJSSD/article/view/368
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author Ayana Melaku Yadessa
Digafie Zeleke
author_facet Ayana Melaku Yadessa
Digafie Zeleke
author_sort Ayana Melaku Yadessa
collection DOAJ
description Numerous natural products possessing quinoline moiety exhibit interesting biological and pharmacological properties, such as antimalarial, antibacterial, antiasthmatic, antihypertensive, anti-inflammatory, immunosuppressive, antileishmanial, and anticancer  activity. Surprising, quinoline scaffold has been used to synthesize antimalarial, antibacterial and anticancer drugs. This article provides update on the latest development in synthesis and biological evaluation of antimalarial, antibacterial and anticancer quinoline analogs. The new synthetic methodologies and the biological activities of the new quinoline analogs in the three areas were focused. Key words: antimalarial, antibacterial, anticancer and quinoline
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spelling doaj.art-8914d0b15cc94884b230df087e533ceb2022-12-21T20:13:25ZengAdama Science and Technology UniversityEthiopian Journal of Science and Sustainable Development1998-05312663-32052021-06-018210.20372/ejssdastu:v8.i2.2021.368A Review on Synthesis of Quinoline Analogs as Antimalarial, Antibacterial and Anticancer agentsAyana Melaku Yadessa0Digafie Zeleke1Department of Chemistry, School of Applied Natural Sciences, Adama Science and Technology University, Ethiopia; Email: yadessamelaku2010@gmail.comAdama Science and Technology UniversityNumerous natural products possessing quinoline moiety exhibit interesting biological and pharmacological properties, such as antimalarial, antibacterial, antiasthmatic, antihypertensive, anti-inflammatory, immunosuppressive, antileishmanial, and anticancer  activity. Surprising, quinoline scaffold has been used to synthesize antimalarial, antibacterial and anticancer drugs. This article provides update on the latest development in synthesis and biological evaluation of antimalarial, antibacterial and anticancer quinoline analogs. The new synthetic methodologies and the biological activities of the new quinoline analogs in the three areas were focused. Key words: antimalarial, antibacterial, anticancer and quinolinehttps://ejssd.astu.edu.et/index.php/EJSSD/article/view/368
spellingShingle Ayana Melaku Yadessa
Digafie Zeleke
A Review on Synthesis of Quinoline Analogs as Antimalarial, Antibacterial and Anticancer agents
Ethiopian Journal of Science and Sustainable Development
title A Review on Synthesis of Quinoline Analogs as Antimalarial, Antibacterial and Anticancer agents
title_full A Review on Synthesis of Quinoline Analogs as Antimalarial, Antibacterial and Anticancer agents
title_fullStr A Review on Synthesis of Quinoline Analogs as Antimalarial, Antibacterial and Anticancer agents
title_full_unstemmed A Review on Synthesis of Quinoline Analogs as Antimalarial, Antibacterial and Anticancer agents
title_short A Review on Synthesis of Quinoline Analogs as Antimalarial, Antibacterial and Anticancer agents
title_sort review on synthesis of quinoline analogs as antimalarial antibacterial and anticancer agents
url https://ejssd.astu.edu.et/index.php/EJSSD/article/view/368
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