A Review on Synthesis of Quinoline Analogs as Antimalarial, Antibacterial and Anticancer agents
Numerous natural products possessing quinoline moiety exhibit interesting biological and pharmacological properties, such as antimalarial, antibacterial, antiasthmatic, antihypertensive, anti-inflammatory, immunosuppressive, antileishmanial, and anticancer activity. Surprising, quinoline scaffold h...
Main Authors: | , |
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Format: | Article |
Language: | English |
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Adama Science and Technology University
2021-06-01
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Series: | Ethiopian Journal of Science and Sustainable Development |
Online Access: | https://ejssd.astu.edu.et/index.php/EJSSD/article/view/368 |
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author | Ayana Melaku Yadessa Digafie Zeleke |
author_facet | Ayana Melaku Yadessa Digafie Zeleke |
author_sort | Ayana Melaku Yadessa |
collection | DOAJ |
description | Numerous natural products possessing quinoline moiety exhibit interesting biological and pharmacological properties, such as antimalarial, antibacterial, antiasthmatic, antihypertensive, anti-inflammatory, immunosuppressive, antileishmanial, and anticancer activity. Surprising, quinoline scaffold has been used to synthesize antimalarial, antibacterial and anticancer drugs. This article provides update on the latest development in synthesis and biological evaluation of antimalarial, antibacterial and anticancer quinoline analogs. The new synthetic methodologies and the biological activities of the new quinoline analogs in the three areas were focused.
Key words: antimalarial, antibacterial, anticancer and quinoline |
first_indexed | 2024-12-19T16:56:05Z |
format | Article |
id | doaj.art-8914d0b15cc94884b230df087e533ceb |
institution | Directory Open Access Journal |
issn | 1998-0531 2663-3205 |
language | English |
last_indexed | 2024-12-19T16:56:05Z |
publishDate | 2021-06-01 |
publisher | Adama Science and Technology University |
record_format | Article |
series | Ethiopian Journal of Science and Sustainable Development |
spelling | doaj.art-8914d0b15cc94884b230df087e533ceb2022-12-21T20:13:25ZengAdama Science and Technology UniversityEthiopian Journal of Science and Sustainable Development1998-05312663-32052021-06-018210.20372/ejssdastu:v8.i2.2021.368A Review on Synthesis of Quinoline Analogs as Antimalarial, Antibacterial and Anticancer agentsAyana Melaku Yadessa0Digafie Zeleke1Department of Chemistry, School of Applied Natural Sciences, Adama Science and Technology University, Ethiopia; Email: yadessamelaku2010@gmail.comAdama Science and Technology UniversityNumerous natural products possessing quinoline moiety exhibit interesting biological and pharmacological properties, such as antimalarial, antibacterial, antiasthmatic, antihypertensive, anti-inflammatory, immunosuppressive, antileishmanial, and anticancer activity. Surprising, quinoline scaffold has been used to synthesize antimalarial, antibacterial and anticancer drugs. This article provides update on the latest development in synthesis and biological evaluation of antimalarial, antibacterial and anticancer quinoline analogs. The new synthetic methodologies and the biological activities of the new quinoline analogs in the three areas were focused. Key words: antimalarial, antibacterial, anticancer and quinolinehttps://ejssd.astu.edu.et/index.php/EJSSD/article/view/368 |
spellingShingle | Ayana Melaku Yadessa Digafie Zeleke A Review on Synthesis of Quinoline Analogs as Antimalarial, Antibacterial and Anticancer agents Ethiopian Journal of Science and Sustainable Development |
title | A Review on Synthesis of Quinoline Analogs as Antimalarial, Antibacterial and Anticancer agents |
title_full | A Review on Synthesis of Quinoline Analogs as Antimalarial, Antibacterial and Anticancer agents |
title_fullStr | A Review on Synthesis of Quinoline Analogs as Antimalarial, Antibacterial and Anticancer agents |
title_full_unstemmed | A Review on Synthesis of Quinoline Analogs as Antimalarial, Antibacterial and Anticancer agents |
title_short | A Review on Synthesis of Quinoline Analogs as Antimalarial, Antibacterial and Anticancer agents |
title_sort | review on synthesis of quinoline analogs as antimalarial antibacterial and anticancer agents |
url | https://ejssd.astu.edu.et/index.php/EJSSD/article/view/368 |
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