Conserved enhancers control notochord expression of vertebrate Brachyury
Abstract The cell type-specific expression of key transcription factors is central to development and disease. Brachyury/T/TBXT is a major transcription factor for gastrulation, tailbud patterning, and notochord formation; however, how its expression is controlled in the mammalian notochord has rema...
Main Authors: | Cassie L. Kemmler, Jana Smolikova, Hannah R. Moran, Brandon J. Mannion, Dunja Knapp, Fabian Lim, Anna Czarkwiani, Viviana Hermosilla Aguayo, Vincent Rapp, Olivia E. Fitch, Seraina Bötschi, Licia Selleri, Emma Farley, Ingo Braasch, Maximina Yun, Axel Visel, Marco Osterwalder, Christian Mosimann, Zbynek Kozmik, Alexa Burger |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-10-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-42151-3 |
Similar Items
-
Xbp1 and Brachyury establish an evolutionarily conserved subcircuit of the notochord gene regulatory network
by: Yushi Wu, et al.
Published: (2022-01-01) -
Snail Transcriptionally Represses <i>Brachyury</i> to Promote the Mesenchymal-Epithelial Transition in Ascidian Notochord Cells
by: Bingtong Wu, et al.
Published: (2024-03-01) -
Diverse logics and grammar encode notochord enhancers
by: Benjamin P. Song, et al.
Published: (2023-02-01) -
Origin of the Chordate Notochord
by: Zihao Sui, et al.
Published: (2021-09-01) -
Eph regulates dorsoventral asymmetry of the notochord plate and convergent extension-mediated notochord formation.
by: Izumi Oda-Ishii, et al.
Published: (2010-10-01)