Differential Contribution of N- and C-Terminal Regions of HIF1α and HIF2α to Their Target Gene Selectivity

Differential Contribution of N- and C-Terminal Regions of HIF1α and HIF2α to Their Target Gene Selectivity

Cellular response to hypoxia is controlled by the hypoxia-inducible transcription factors HIF1α and HIF2α. Some genes are preferentially induced by HIF1α or HIF2α, as has been explored in some cell models and for particular sets of genes. Here we have extended this analysis to other HIF-dependent ge...

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Bibliographic Details
Main Authors: Antonio Bouthelier, Florinda Meléndez-Rodríguez, Andrés A. Urrutia, Julián Aragonés
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
oxygen
hypoxia-inducible factors
HIF1
HIF2
transcription
Online Access:https://www.mdpi.com/1422-0067/21/24/9401

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