Anaphylaxis in Children and Adolescents: Greek Data Analysis from the European Anaphylaxis Registry (NORA)

The European Anaphylaxis Registry (NORA) was designed in order to create a comprehensive Anaphylaxis Registry regarding anaphylactic reactions characteristics and management in several European countries, including Greece. This study aims to analyze Greek data obtained in the NORA framework and desc...

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Main Authors: Nikolaos Pyrpyris, Maria Kritikou, Xenofon Aggelidis, Ioanna Manolaraki, Michael Makris, Nikolaos G. Papadopoulos, Paraskevi Xepapadaki
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Journal of Personalized Medicine
Subjects:
Online Access:https://www.mdpi.com/2075-4426/12/10/1614
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author Nikolaos Pyrpyris
Maria Kritikou
Xenofon Aggelidis
Ioanna Manolaraki
Michael Makris
Nikolaos G. Papadopoulos
Paraskevi Xepapadaki
author_facet Nikolaos Pyrpyris
Maria Kritikou
Xenofon Aggelidis
Ioanna Manolaraki
Michael Makris
Nikolaos G. Papadopoulos
Paraskevi Xepapadaki
author_sort Nikolaos Pyrpyris
collection DOAJ
description The European Anaphylaxis Registry (NORA) was designed in order to create a comprehensive Anaphylaxis Registry regarding anaphylactic reactions characteristics and management in several European countries, including Greece. This study aims to analyze Greek data obtained in the NORA framework and describe anaphylaxis’ characteristics in this pediatric cohort. An online questionnaire was filled out by the Allergy Unit of the 2nd Pediatric Department of NKUA, regarding reported anaphylaxis characteristics. A total of 284 pediatric patients were analyzed. Patients were predominantly male. A previous, mild reaction (59.5%) to the same allergen was documented in 44.4% of patients. The most common system involved was skin and/or mucosa, followed by the respiratory system. Food was the most common eliciting factor (82.4%). First line treatment was most administered solely by a healthcare professional, followed by a lay person (38.7%). Auto injected adrenaline use by lay persons was third in frequency (29.2%). Most patients received post-reaction counseling and appropriate drug prescription. This study provides insight in anaphylactic cases’ characteristics and management in a Greek pediatric cohort. A low rate of adrenaline autoinjector administration was noted in lay people; however, drug prescription and counseling following the reaction could help increase correct acute anaphylaxis management in the future.
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spelling doaj.art-891dc85b82bd48f19ae8cc7771c55c6f2023-11-24T00:49:17ZengMDPI AGJournal of Personalized Medicine2075-44262022-09-011210161410.3390/jpm12101614Anaphylaxis in Children and Adolescents: Greek Data Analysis from the European Anaphylaxis Registry (NORA)Nikolaos Pyrpyris0Maria Kritikou1Xenofon Aggelidis2Ioanna Manolaraki3Michael Makris4Nikolaos G. Papadopoulos5Paraskevi Xepapadaki6Allergy and Clinical Immunology Unit, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, 115 27 Athens, GreeceAllergy and Clinical Immunology Unit, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, 115 27 Athens, GreeceAllergy Unit, 2nd Department of Dermatology and Venereology, Attikon University Hospital, National and Kapodistrian University of Athens, 124 62 Athens, GreeceAllergy and Clinical Immunology Unit, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, 115 27 Athens, GreeceAllergy Unit, 2nd Department of Dermatology and Venereology, Attikon University Hospital, National and Kapodistrian University of Athens, 124 62 Athens, GreeceAllergy and Clinical Immunology Unit, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, 115 27 Athens, GreeceAllergy and Clinical Immunology Unit, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, 115 27 Athens, GreeceThe European Anaphylaxis Registry (NORA) was designed in order to create a comprehensive Anaphylaxis Registry regarding anaphylactic reactions characteristics and management in several European countries, including Greece. This study aims to analyze Greek data obtained in the NORA framework and describe anaphylaxis’ characteristics in this pediatric cohort. An online questionnaire was filled out by the Allergy Unit of the 2nd Pediatric Department of NKUA, regarding reported anaphylaxis characteristics. A total of 284 pediatric patients were analyzed. Patients were predominantly male. A previous, mild reaction (59.5%) to the same allergen was documented in 44.4% of patients. The most common system involved was skin and/or mucosa, followed by the respiratory system. Food was the most common eliciting factor (82.4%). First line treatment was most administered solely by a healthcare professional, followed by a lay person (38.7%). Auto injected adrenaline use by lay persons was third in frequency (29.2%). Most patients received post-reaction counseling and appropriate drug prescription. This study provides insight in anaphylactic cases’ characteristics and management in a Greek pediatric cohort. A low rate of adrenaline autoinjector administration was noted in lay people; however, drug prescription and counseling following the reaction could help increase correct acute anaphylaxis management in the future.https://www.mdpi.com/2075-4426/12/10/1614anaphylaxisfood allergyanaphylaxis management
spellingShingle Nikolaos Pyrpyris
Maria Kritikou
Xenofon Aggelidis
Ioanna Manolaraki
Michael Makris
Nikolaos G. Papadopoulos
Paraskevi Xepapadaki
Anaphylaxis in Children and Adolescents: Greek Data Analysis from the European Anaphylaxis Registry (NORA)
Journal of Personalized Medicine
anaphylaxis
food allergy
anaphylaxis management
title Anaphylaxis in Children and Adolescents: Greek Data Analysis from the European Anaphylaxis Registry (NORA)
title_full Anaphylaxis in Children and Adolescents: Greek Data Analysis from the European Anaphylaxis Registry (NORA)
title_fullStr Anaphylaxis in Children and Adolescents: Greek Data Analysis from the European Anaphylaxis Registry (NORA)
title_full_unstemmed Anaphylaxis in Children and Adolescents: Greek Data Analysis from the European Anaphylaxis Registry (NORA)
title_short Anaphylaxis in Children and Adolescents: Greek Data Analysis from the European Anaphylaxis Registry (NORA)
title_sort anaphylaxis in children and adolescents greek data analysis from the european anaphylaxis registry nora
topic anaphylaxis
food allergy
anaphylaxis management
url https://www.mdpi.com/2075-4426/12/10/1614
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