Reptin regulates DNA double strand breaks repair in human hepatocellular carcinoma.

Reptin/RUVBL2 is overexpressed in most hepatocellular carcinomas and is required for the growth and viability of HCC cells. Reptin is involved in several chromatin remodeling complexes, some of which are involved in the detection and repair of DNA damage, but data on Reptin involvement in the repair...

Full description

Bibliographic Details
Main Authors: Anne-Aurélie Raymond, Samira Benhamouche, Véronique Neaud, Julie Di Martino, Joaquim Javary, Jean Rosenbaum
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4398330?pdf=render