Kidney transplantation in children: a 50-case experience

OBJECTIVES: The aim of this article was to report our experience with kidney transplantation in children. MATERIALS AND METHODS: From June 1980 to December 2003, 690 kidney transplants were performed in our institution, among which 50 were in patients with less than 18 years old. Technical aspects a...

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Main Authors: Miguel Zerati Filho, Paulo S. Furtado, Ubirajara Barroso Jr, Cassio M. Pugas, Cleverson D'avila, Geovanne F. Souza
Format: Article
Language:English
Published: Sociedade Brasileira de Urologia 2005-12-01
Series:International Brazilian Journal of Urology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382005000600009
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author Miguel Zerati Filho
Paulo S. Furtado
Ubirajara Barroso Jr
Cassio M. Pugas
Cleverson D'avila
Geovanne F. Souza
author_facet Miguel Zerati Filho
Paulo S. Furtado
Ubirajara Barroso Jr
Cassio M. Pugas
Cleverson D'avila
Geovanne F. Souza
author_sort Miguel Zerati Filho
collection DOAJ
description OBJECTIVES: The aim of this article was to report our experience with kidney transplantation in children. MATERIALS AND METHODS: From June 1980 to December 2003, 690 kidney transplants were performed in our institution, among which 50 were in patients with less than 18 years old. Technical aspects as well as clinical and surgical evolution were reviewed in this study. RESULTS: Patient's mean age was 12 years (2-17 years). Twenty-nine patients were male and 21 female. Live related donors were responsible for 75% of the cases (38 patients) and 25% (12 patients) came from cadaver donors. The main complications were ureteral fistula in 6 patients (12%), arterial stenosis in 2 (4%), wall infection and dehiscence in 1 case (2%). The overall rate of surgical complication was 20%. No case of hyperacute rejection was reported. During the follow-up 20 grafts were lost due to chronic rejection and 2 patients died. No loss of graft due to surgical complications was reported. The graft survival rate was 71% in 1 year, 64% in 3 years and 57% in 5-year follow-up. CONCLUSIONS: Kidney transplantation in children is a viable treatment option for terminal kidney disease presenting success and surgical complication rate similar to kidney transplantation in adults.
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spelling doaj.art-8926e2854217412a8313a444ef5a97782022-12-21T22:32:31ZengSociedade Brasileira de UrologiaInternational Brazilian Journal of Urology1677-55381677-61192005-12-0131655856110.1590/S1677-55382005000600009Kidney transplantation in children: a 50-case experienceMiguel Zerati FilhoPaulo S. FurtadoUbirajara Barroso JrCassio M. PugasCleverson D'avilaGeovanne F. SouzaOBJECTIVES: The aim of this article was to report our experience with kidney transplantation in children. MATERIALS AND METHODS: From June 1980 to December 2003, 690 kidney transplants were performed in our institution, among which 50 were in patients with less than 18 years old. Technical aspects as well as clinical and surgical evolution were reviewed in this study. RESULTS: Patient's mean age was 12 years (2-17 years). Twenty-nine patients were male and 21 female. Live related donors were responsible for 75% of the cases (38 patients) and 25% (12 patients) came from cadaver donors. The main complications were ureteral fistula in 6 patients (12%), arterial stenosis in 2 (4%), wall infection and dehiscence in 1 case (2%). The overall rate of surgical complication was 20%. No case of hyperacute rejection was reported. During the follow-up 20 grafts were lost due to chronic rejection and 2 patients died. No loss of graft due to surgical complications was reported. The graft survival rate was 71% in 1 year, 64% in 3 years and 57% in 5-year follow-up. CONCLUSIONS: Kidney transplantation in children is a viable treatment option for terminal kidney disease presenting success and surgical complication rate similar to kidney transplantation in adults.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382005000600009kidney transplantationchildrencomplicationsgraft survival
spellingShingle Miguel Zerati Filho
Paulo S. Furtado
Ubirajara Barroso Jr
Cassio M. Pugas
Cleverson D'avila
Geovanne F. Souza
Kidney transplantation in children: a 50-case experience
International Brazilian Journal of Urology
kidney transplantation
children
complications
graft survival
title Kidney transplantation in children: a 50-case experience
title_full Kidney transplantation in children: a 50-case experience
title_fullStr Kidney transplantation in children: a 50-case experience
title_full_unstemmed Kidney transplantation in children: a 50-case experience
title_short Kidney transplantation in children: a 50-case experience
title_sort kidney transplantation in children a 50 case experience
topic kidney transplantation
children
complications
graft survival
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382005000600009
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AT paulosfurtado kidneytransplantationinchildrena50caseexperience
AT ubirajarabarrosojr kidneytransplantationinchildrena50caseexperience
AT cassiompugas kidneytransplantationinchildrena50caseexperience
AT cleversondavila kidneytransplantationinchildrena50caseexperience
AT geovannefsouza kidneytransplantationinchildrena50caseexperience