Fungal Septic Knee Arthritis Caused by <i>Aspergillus fumigatus</i> following Anterior Cruciate Ligament Reconstruction
Postoperative infections after arthroscopic anterior cruciate ligament (ACL) reconstruction (ACLR) represent a rare but severe complication. An extremely rare case of <i>Aspergillus</i> septic arthritis in a 27-year-old patient following arthroscopic ACLR is reported. The patient present...
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MDPI AG
2021-10-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/11/11/1975 |
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| author | George Samonis Christos Koutserimpas Georgia Vrioni Elsa Kampos Martinez Panagiotis Kouloumentas Kalliopi Alpantaki George Saroglou |
| author_facet | George Samonis Christos Koutserimpas Georgia Vrioni Elsa Kampos Martinez Panagiotis Kouloumentas Kalliopi Alpantaki George Saroglou |
| author_sort | George Samonis |
| collection | DOAJ |
| description | Postoperative infections after arthroscopic anterior cruciate ligament (ACL) reconstruction (ACLR) represent a rare but severe complication. An extremely rare case of <i>Aspergillus</i> septic arthritis in a 27-year-old patient following arthroscopic ACLR is reported. The patient presented with signs of knee infection 14 days after ACLR. Two consecutive arthroscopic debridements were performed, while eventually histopathology, cultures and multiplex PCR test revealed <i>Aspergillus</i> identified as <i>A. fumigatus</i> by mass spectrometry. The patient commenced long-term treatment with voriconazole. Fungal arthritis or osteomyelitis following ACLR has a mild local and general inflammatory reaction when compared to the bacterial ones. Nevertheless, such infections may lead to aggressive osseous destruction and necrosis. A high index of suspicion is of utmost importance for early detection, while microscopic, histological examination and multiplex PCR may be more helpful for the diagnosis than cultures since cultures are more time-consuming and may vary depending on different factors. |
| first_indexed | 2024-03-10T05:34:35Z |
| format | Article |
| id | doaj.art-89276fc4032b43038b3ecf52f47cc2f2 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T05:34:35Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-89276fc4032b43038b3ecf52f47cc2f22023-11-22T23:00:32ZengMDPI AGDiagnostics2075-44182021-10-011111197510.3390/diagnostics11111975Fungal Septic Knee Arthritis Caused by <i>Aspergillus fumigatus</i> following Anterior Cruciate Ligament ReconstructionGeorge Samonis0Christos Koutserimpas1Georgia Vrioni2Elsa Kampos Martinez3Panagiotis Kouloumentas4Kalliopi Alpantaki5George Saroglou6Department of Internal Medicine, University Hospital of Heraklion, Crete, 71500 Heraklion, GreeceDepartment of Orthopaedics and Traumatology, “251” Hellenic Air Force General Hospital of Athens, 11525 Athens, GreeceDepartment of Microbiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece“Metropolitan” General Hospital, N. Faliron, 18547 Athens, Greece“Metropolitan” General Hospital, N. Faliron, 18547 Athens, GreeceDepartment of Orthopaedics and Traumatology, “Venizeleion” General Hospital of Heraklion, Crete, 71409 Heraklion, Greece“Metropolitan” General Hospital, N. Faliron, 18547 Athens, GreecePostoperative infections after arthroscopic anterior cruciate ligament (ACL) reconstruction (ACLR) represent a rare but severe complication. An extremely rare case of <i>Aspergillus</i> septic arthritis in a 27-year-old patient following arthroscopic ACLR is reported. The patient presented with signs of knee infection 14 days after ACLR. Two consecutive arthroscopic debridements were performed, while eventually histopathology, cultures and multiplex PCR test revealed <i>Aspergillus</i> identified as <i>A. fumigatus</i> by mass spectrometry. The patient commenced long-term treatment with voriconazole. Fungal arthritis or osteomyelitis following ACLR has a mild local and general inflammatory reaction when compared to the bacterial ones. Nevertheless, such infections may lead to aggressive osseous destruction and necrosis. A high index of suspicion is of utmost importance for early detection, while microscopic, histological examination and multiplex PCR may be more helpful for the diagnosis than cultures since cultures are more time-consuming and may vary depending on different factors.https://www.mdpi.com/2075-4418/11/11/1975<i>Aspergillus</i> arthritisfungal arthritisknee infectionanterior cruciate ligament infection |
| spellingShingle | George Samonis Christos Koutserimpas Georgia Vrioni Elsa Kampos Martinez Panagiotis Kouloumentas Kalliopi Alpantaki George Saroglou Fungal Septic Knee Arthritis Caused by <i>Aspergillus fumigatus</i> following Anterior Cruciate Ligament Reconstruction Diagnostics <i>Aspergillus</i> arthritis fungal arthritis knee infection anterior cruciate ligament infection |
| title | Fungal Septic Knee Arthritis Caused by <i>Aspergillus fumigatus</i> following Anterior Cruciate Ligament Reconstruction |
| title_full | Fungal Septic Knee Arthritis Caused by <i>Aspergillus fumigatus</i> following Anterior Cruciate Ligament Reconstruction |
| title_fullStr | Fungal Septic Knee Arthritis Caused by <i>Aspergillus fumigatus</i> following Anterior Cruciate Ligament Reconstruction |
| title_full_unstemmed | Fungal Septic Knee Arthritis Caused by <i>Aspergillus fumigatus</i> following Anterior Cruciate Ligament Reconstruction |
| title_short | Fungal Septic Knee Arthritis Caused by <i>Aspergillus fumigatus</i> following Anterior Cruciate Ligament Reconstruction |
| title_sort | fungal septic knee arthritis caused by i aspergillus fumigatus i following anterior cruciate ligament reconstruction |
| topic | <i>Aspergillus</i> arthritis fungal arthritis knee infection anterior cruciate ligament infection |
| url | https://www.mdpi.com/2075-4418/11/11/1975 |
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