Is Resting State Functional MRI Effective Connectivity in Movement Disorders Helpful? A Focused Review Across Lifespan and Disease
In the evolving modern era of neuromodulation for movement disorders in adults and children, much progress has been made recently characterizing the human motor network (MN) with potentially important treatment implications. Herein is a focused review of relevant resting state fMRI functional and ef...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-04-01
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| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2022.847834/full |
| _version_ | 1811335195398242304 |
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| author | Bethany L. Sussman Sarah N. Wyckoff Sarah N. Wyckoff Jennifer Heim Angus A. Wilfong P. David Adelson Michael C. Kruer Michael C. Kruer Maria Jose Gonzalez Varina L. Boerwinkle |
| author_facet | Bethany L. Sussman Sarah N. Wyckoff Sarah N. Wyckoff Jennifer Heim Angus A. Wilfong P. David Adelson Michael C. Kruer Michael C. Kruer Maria Jose Gonzalez Varina L. Boerwinkle |
| author_sort | Bethany L. Sussman |
| collection | DOAJ |
| description | In the evolving modern era of neuromodulation for movement disorders in adults and children, much progress has been made recently characterizing the human motor network (MN) with potentially important treatment implications. Herein is a focused review of relevant resting state fMRI functional and effective connectivity of the human motor network across the lifespan in health and disease. The goal is to examine how the transition from functional connectivity to dynamic effective connectivity may be especially informative of network-targeted movement disorder therapies, with hopeful implications for children. |
| first_indexed | 2024-04-13T17:20:34Z |
| format | Article |
| id | doaj.art-89277aa6cdcf4537aa0f64d7db414b1d |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-13T17:20:34Z |
| publishDate | 2022-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-89277aa6cdcf4537aa0f64d7db414b1d2022-12-22T02:38:00ZengFrontiers Media S.A.Frontiers in Neurology1664-22952022-04-011310.3389/fneur.2022.847834847834Is Resting State Functional MRI Effective Connectivity in Movement Disorders Helpful? A Focused Review Across Lifespan and DiseaseBethany L. Sussman0Sarah N. Wyckoff1Sarah N. Wyckoff2Jennifer Heim3Angus A. Wilfong4P. David Adelson5Michael C. Kruer6Michael C. Kruer7Maria Jose Gonzalez8Varina L. Boerwinkle9Division of Neuroscience, Barrow Neurological Institute at Phoenix Children's Hospital, Phoenix, AZ, United StatesDivision of Neuroscience, Barrow Neurological Institute at Phoenix Children's Hospital, Phoenix, AZ, United StatesDepartment of Research, Phoenix Children's Hospital, Phoenix, AZ, United StatesDivision of Pediatric Neurology, Barrow Neurological Institute at Phoenix Children's Hospital, Phoenix, AZ, United StatesDivision of Pediatric Neurology, Barrow Neurological Institute at Phoenix Children's Hospital, Phoenix, AZ, United StatesDivision of Pediatric Neurosurgery, Barrow Neurological Institute at Phoenix Children's Hospital, Phoenix, AZ, United StatesDivision of Pediatric Neurology, Barrow Neurological Institute at Phoenix Children's Hospital, Phoenix, AZ, United StatesDepartments of Child Health, Neurology, Genetics and Cellular & Molecular Medicine, University of Arizona College of Medicine – Phoenix, Phoenix, AZ, United StatesDepartments of Pediatrics, SBH Health System, Bronx, NY, United StatesDivision of Pediatric Neurology, Barrow Neurological Institute at Phoenix Children's Hospital, Phoenix, AZ, United StatesIn the evolving modern era of neuromodulation for movement disorders in adults and children, much progress has been made recently characterizing the human motor network (MN) with potentially important treatment implications. Herein is a focused review of relevant resting state fMRI functional and effective connectivity of the human motor network across the lifespan in health and disease. The goal is to examine how the transition from functional connectivity to dynamic effective connectivity may be especially informative of network-targeted movement disorder therapies, with hopeful implications for children.https://www.frontiersin.org/articles/10.3389/fneur.2022.847834/fullresting state functional MRIeffective connectivitydystoniamovement disorderssubcorticalbasal ganglia |
| spellingShingle | Bethany L. Sussman Sarah N. Wyckoff Sarah N. Wyckoff Jennifer Heim Angus A. Wilfong P. David Adelson Michael C. Kruer Michael C. Kruer Maria Jose Gonzalez Varina L. Boerwinkle Is Resting State Functional MRI Effective Connectivity in Movement Disorders Helpful? A Focused Review Across Lifespan and Disease Frontiers in Neurology resting state functional MRI effective connectivity dystonia movement disorders subcortical basal ganglia |
| title | Is Resting State Functional MRI Effective Connectivity in Movement Disorders Helpful? A Focused Review Across Lifespan and Disease |
| title_full | Is Resting State Functional MRI Effective Connectivity in Movement Disorders Helpful? A Focused Review Across Lifespan and Disease |
| title_fullStr | Is Resting State Functional MRI Effective Connectivity in Movement Disorders Helpful? A Focused Review Across Lifespan and Disease |
| title_full_unstemmed | Is Resting State Functional MRI Effective Connectivity in Movement Disorders Helpful? A Focused Review Across Lifespan and Disease |
| title_short | Is Resting State Functional MRI Effective Connectivity in Movement Disorders Helpful? A Focused Review Across Lifespan and Disease |
| title_sort | is resting state functional mri effective connectivity in movement disorders helpful a focused review across lifespan and disease |
| topic | resting state functional MRI effective connectivity dystonia movement disorders subcortical basal ganglia |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2022.847834/full |
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