Pre-exposure prophylaxis for HIV prevention preferences among young adult African American men who have sex with men.

Pre-exposure prophylaxis (PrEP) is effective in preventing HIV infections among men who have sex with men (MSM). PrEP uptake and adherence remain low and product preferences are unknown, especially among young African American MSM who are most at-risk. We conducted 26 qualitative interviews from 201...

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Main Authors: Rupa R Patel, John S Crane, Julia López, Philip A Chan, Albert Y Liu, Rubabin Tooba, Aimee S James
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0209484
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author Rupa R Patel
John S Crane
Julia López
Philip A Chan
Albert Y Liu
Rubabin Tooba
Aimee S James
author_facet Rupa R Patel
John S Crane
Julia López
Philip A Chan
Albert Y Liu
Rubabin Tooba
Aimee S James
author_sort Rupa R Patel
collection DOAJ
description Pre-exposure prophylaxis (PrEP) is effective in preventing HIV infections among men who have sex with men (MSM). PrEP uptake and adherence remain low and product preferences are unknown, especially among young African American MSM who are most at-risk. We conducted 26 qualitative interviews from 2014-2016 among young adult HIV-negative African American MSM regarding PrEP product preferences in Missouri. While the pill and injectable were most liked of all modalities, about a quarter preferred rectal products or patches. Most participants preferred a long-acting injectable (LAI) to daily oral pills due to better medication adherence and a dislike for taking pills. Many participants preferred daily oral pills to on-demand oral PrEP due to the inability to predict sex and the perception that insufficient time or medication would not achieve HIV protection with on-demand. A fear of needles and the perception that there would not be therapeutic levels for a long duration were concerns with injectable PrEP. Study findings highlight the need for a range of prevention options for African American MSM and can inform PrEP product development as well as dissemination and implementation efforts.
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spelling doaj.art-8929318b369446fda5c1a2f52ab925d72022-12-21T17:34:09ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-011312e020948410.1371/journal.pone.0209484Pre-exposure prophylaxis for HIV prevention preferences among young adult African American men who have sex with men.Rupa R PatelJohn S CraneJulia LópezPhilip A ChanAlbert Y LiuRubabin ToobaAimee S JamesPre-exposure prophylaxis (PrEP) is effective in preventing HIV infections among men who have sex with men (MSM). PrEP uptake and adherence remain low and product preferences are unknown, especially among young African American MSM who are most at-risk. We conducted 26 qualitative interviews from 2014-2016 among young adult HIV-negative African American MSM regarding PrEP product preferences in Missouri. While the pill and injectable were most liked of all modalities, about a quarter preferred rectal products or patches. Most participants preferred a long-acting injectable (LAI) to daily oral pills due to better medication adherence and a dislike for taking pills. Many participants preferred daily oral pills to on-demand oral PrEP due to the inability to predict sex and the perception that insufficient time or medication would not achieve HIV protection with on-demand. A fear of needles and the perception that there would not be therapeutic levels for a long duration were concerns with injectable PrEP. Study findings highlight the need for a range of prevention options for African American MSM and can inform PrEP product development as well as dissemination and implementation efforts.https://doi.org/10.1371/journal.pone.0209484
spellingShingle Rupa R Patel
John S Crane
Julia López
Philip A Chan
Albert Y Liu
Rubabin Tooba
Aimee S James
Pre-exposure prophylaxis for HIV prevention preferences among young adult African American men who have sex with men.
PLoS ONE
title Pre-exposure prophylaxis for HIV prevention preferences among young adult African American men who have sex with men.
title_full Pre-exposure prophylaxis for HIV prevention preferences among young adult African American men who have sex with men.
title_fullStr Pre-exposure prophylaxis for HIV prevention preferences among young adult African American men who have sex with men.
title_full_unstemmed Pre-exposure prophylaxis for HIV prevention preferences among young adult African American men who have sex with men.
title_short Pre-exposure prophylaxis for HIV prevention preferences among young adult African American men who have sex with men.
title_sort pre exposure prophylaxis for hiv prevention preferences among young adult african american men who have sex with men
url https://doi.org/10.1371/journal.pone.0209484
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