Estrogen Receptor Is Required for Metformin-Induced Apoptosis in Breast Cancer Cells Under Hyperglycemic Conditions

Backgrounds: About 25% to 30% of estrogen receptor (ER)-positive breast cancer patients develop resistance to endocrine therapy. Human epidermal growth factor receptor 2 (HER2) has been shown to cooperate with several growth factors that regulate cellular energy metabolism, including the insulin-lik...

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Bibliographic Details
Main Authors: Andisyah Putri Sekar, Septia Nurmala, Eiji Matsuura, Xian Wen Tan, Ratika Rahmasari, Rani Sauriasari
Format: Article
Language:English
Published: SAGE Publishing 2024-04-01
Series:Breast Cancer: Basic and Clinical Research
Online Access:https://doi.org/10.1177/11782234241240173