Granulomatous slack skin: a rare subtype of mycosis fungoides
Abstract: We report a case of granulomatous slack skin, a rare and indolent subtype of mycosis fungoides. It affects mainly men between the third and fourth decades. It is characterized by hardened and erithematous plaques that mainly affect flexural areas and become pedunculated after some years. H...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Dermatologia
2017-10-01
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| Series: | Anais Brasileiros de Dermatologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000500694&tlng=en |
| _version_ | 1819005478841090048 |
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| author | Letícia Marra da Motta Cleverson Teixeira Soares Sadamitsu Nakandakari Gardênia Viana da Silva Maria Helena Mazzi Freire Nigro Leticia Stella Gardini Brandão |
| author_facet | Letícia Marra da Motta Cleverson Teixeira Soares Sadamitsu Nakandakari Gardênia Viana da Silva Maria Helena Mazzi Freire Nigro Leticia Stella Gardini Brandão |
| author_sort | Letícia Marra da Motta |
| collection | DOAJ |
| description | Abstract: We report a case of granulomatous slack skin, a rare and indolent subtype of mycosis fungoides. It affects mainly men between the third and fourth decades. It is characterized by hardened and erithematous plaques that mainly affect flexural areas and become pedunculated after some years. Histological examination shows a dense infiltrate of small atypical lymphocytes involving the dermis (and sometimes the subcutaneous tissue) associated with histiocytic and multinucleated giant cells containing lymphocytes and elastic fibers (lymphophagocytosis and elastophagocytosis, respectively). Patients affected by this entity can develop secondary lymphomas. There are several but little effective therapeutic modalities described. Despite the indolent behavior of granulomatous slack skin, its early recognition and continuous monitoring by a dermatologist becomes essential for its management and prevention of an unfavorable outcome. |
| first_indexed | 2024-12-20T23:53:26Z |
| format | Article |
| id | doaj.art-892b088f32e54a73b9f438127a698150 |
| institution | Directory Open Access Journal |
| issn | 0365-0596 |
| language | English |
| last_indexed | 2024-12-20T23:53:26Z |
| publishDate | 2017-10-01 |
| publisher | Sociedade Brasileira de Dermatologia |
| record_format | Article |
| series | Anais Brasileiros de Dermatologia |
| spelling | doaj.art-892b088f32e54a73b9f438127a6981502022-12-21T19:22:48ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962017-10-0192569469710.1590/abd1806-4841.20175099Granulomatous slack skin: a rare subtype of mycosis fungoidesLetícia Marra da MottaCleverson Teixeira SoaresSadamitsu NakandakariGardênia Viana da SilvaMaria Helena Mazzi Freire NigroLeticia Stella Gardini BrandãoAbstract: We report a case of granulomatous slack skin, a rare and indolent subtype of mycosis fungoides. It affects mainly men between the third and fourth decades. It is characterized by hardened and erithematous plaques that mainly affect flexural areas and become pedunculated after some years. Histological examination shows a dense infiltrate of small atypical lymphocytes involving the dermis (and sometimes the subcutaneous tissue) associated with histiocytic and multinucleated giant cells containing lymphocytes and elastic fibers (lymphophagocytosis and elastophagocytosis, respectively). Patients affected by this entity can develop secondary lymphomas. There are several but little effective therapeutic modalities described. Despite the indolent behavior of granulomatous slack skin, its early recognition and continuous monitoring by a dermatologist becomes essential for its management and prevention of an unfavorable outcome.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000500694&tlng=encutaneous T-cell lymphomaLymphoproliferative disordersMycosis fungoides |
| spellingShingle | Letícia Marra da Motta Cleverson Teixeira Soares Sadamitsu Nakandakari Gardênia Viana da Silva Maria Helena Mazzi Freire Nigro Leticia Stella Gardini Brandão Granulomatous slack skin: a rare subtype of mycosis fungoides Anais Brasileiros de Dermatologia cutaneous T-cell lymphoma Lymphoproliferative disorders Mycosis fungoides |
| title | Granulomatous slack skin: a rare subtype of mycosis fungoides |
| title_full | Granulomatous slack skin: a rare subtype of mycosis fungoides |
| title_fullStr | Granulomatous slack skin: a rare subtype of mycosis fungoides |
| title_full_unstemmed | Granulomatous slack skin: a rare subtype of mycosis fungoides |
| title_short | Granulomatous slack skin: a rare subtype of mycosis fungoides |
| title_sort | granulomatous slack skin a rare subtype of mycosis fungoides |
| topic | cutaneous T-cell lymphoma Lymphoproliferative disorders Mycosis fungoides |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000500694&tlng=en |
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