P45 forms a complex with FADD and promotes neuronal cell survival following spinal cord injury.

P45 forms a complex with FADD and promotes neuronal cell survival following spinal cord injury.

Fas-associated death domain (DD) adaptor (FADD), a member of the DD superfamily, contains both a DD and a death effector domain (DED) that are important in mediating FAS ligand-induced apoptotic signaling. P45 is a unique member of the DD superfamily in that it has a domain with sequence and structu...

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Bibliographic Details
Main Authors: Tsung-Chang Sung, Zhijiang Chen, Sandrine Thuret, Marçal Vilar, Fred H Gage, Roland Riek, Kuo-Fen Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3720591?pdf=render

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