New diacyl flavonoid derivatives from the Egyptian plant Blepharis edulis (Forssk.) Pers.

In continuation of our phytochemical investigation of Blepharis edulis (Forssk.) Pers., family Acanthaceae; two new diacyl flavone derivatives: apigenin-7-O-(2″-acetyl-6″-E-p-coumaroyl-β-d-glucopyranoside) (1) and apigenin-7-O-(4″-acetyl-6″-E-p-coumaroyl-β-d-glucopyranoside) (2), along with eight kn...

Full description

Bibliographic Details
Main Author: Mohamed Abdel-Ghaffar Ashour
Format: Article
Language:English
Published: Faculty of Pharmacy, Cairo University 2015-06-01
Series:Bulletin of Faculty of Pharmacy Cairo University
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1110093115000046
Description
Summary:In continuation of our phytochemical investigation of Blepharis edulis (Forssk.) Pers., family Acanthaceae; two new diacyl flavone derivatives: apigenin-7-O-(2″-acetyl-6″-E-p-coumaroyl-β-d-glucopyranoside) (1) and apigenin-7-O-(4″-acetyl-6″-E-p-coumaroyl-β-d-glucopyranoside) (2), along with eight known compounds: apigenin-7-O-(3″-acetyl-6″-E-p-coumaroyl-β-d-glucopyranoside) (3), naringenin-7-O-(3″-acetyl-6″-E-p-coumaroyl-β-d-glucopyranoside) (4), apigenin-7-O-(6″-E-p-coumaroyl-β-d-glucopyranoside) (5), naringenin-7-O-(6″-E-p-coumaroyl-β-d-glucopyranoside) (6), acacetin (7), naringenin (8), vanillic acid (9) and 4-hydroxybenzoic acid (10) were isolated and unambiguously identified from the ether fraction of the total extract of the wild Egyptian species B. edulis (Forssk.), family Acanthaceae. Identification and structure elucidation of the isolated compounds were carried out and confirmed through full data obtained from different 1D and 2D NMR experiments and mass spectral analyses. Compounds 1–9 were isolated for the first time from the species. Compounds 1 and 2 are new natural products isolated herein for the first time in nature.
ISSN:1110-0931