New diacyl flavonoid derivatives from the Egyptian plant Blepharis edulis (Forssk.) Pers.
In continuation of our phytochemical investigation of Blepharis edulis (Forssk.) Pers., family Acanthaceae; two new diacyl flavone derivatives: apigenin-7-O-(2″-acetyl-6″-E-p-coumaroyl-β-d-glucopyranoside) (1) and apigenin-7-O-(4″-acetyl-6″-E-p-coumaroyl-β-d-glucopyranoside) (2), along with eight kn...
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| Format: | Article |
| Language: | English |
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Faculty of Pharmacy, Cairo University
2015-06-01
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| Series: | Bulletin of Faculty of Pharmacy Cairo University |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1110093115000046 |
| _version_ | 1797972387520577536 |
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| author | Mohamed Abdel-Ghaffar Ashour |
| author_facet | Mohamed Abdel-Ghaffar Ashour |
| author_sort | Mohamed Abdel-Ghaffar Ashour |
| collection | DOAJ |
| description | In continuation of our phytochemical investigation of Blepharis edulis (Forssk.) Pers., family Acanthaceae; two new diacyl flavone derivatives: apigenin-7-O-(2″-acetyl-6″-E-p-coumaroyl-β-d-glucopyranoside) (1) and apigenin-7-O-(4″-acetyl-6″-E-p-coumaroyl-β-d-glucopyranoside) (2), along with eight known compounds: apigenin-7-O-(3″-acetyl-6″-E-p-coumaroyl-β-d-glucopyranoside) (3), naringenin-7-O-(3″-acetyl-6″-E-p-coumaroyl-β-d-glucopyranoside) (4), apigenin-7-O-(6″-E-p-coumaroyl-β-d-glucopyranoside) (5), naringenin-7-O-(6″-E-p-coumaroyl-β-d-glucopyranoside) (6), acacetin (7), naringenin (8), vanillic acid (9) and 4-hydroxybenzoic acid (10) were isolated and unambiguously identified from the ether fraction of the total extract of the wild Egyptian species B. edulis (Forssk.), family Acanthaceae. Identification and structure elucidation of the isolated compounds were carried out and confirmed through full data obtained from different 1D and 2D NMR experiments and mass spectral analyses. Compounds 1–9 were isolated for the first time from the species. Compounds 1 and 2 are new natural products isolated herein for the first time in nature. |
| first_indexed | 2024-04-11T03:46:36Z |
| format | Article |
| id | doaj.art-892d4608239f4dac9790f9005159d7ef |
| institution | Directory Open Access Journal |
| issn | 1110-0931 |
| language | English |
| last_indexed | 2024-04-11T03:46:36Z |
| publishDate | 2015-06-01 |
| publisher | Faculty of Pharmacy, Cairo University |
| record_format | Article |
| series | Bulletin of Faculty of Pharmacy Cairo University |
| spelling | doaj.art-892d4608239f4dac9790f9005159d7ef2023-01-02T02:37:51ZengFaculty of Pharmacy, Cairo UniversityBulletin of Faculty of Pharmacy Cairo University1110-09312015-06-01531111710.1016/j.bfopcu.2015.02.001New diacyl flavonoid derivatives from the Egyptian plant Blepharis edulis (Forssk.) Pers.Mohamed Abdel-Ghaffar AshourIn continuation of our phytochemical investigation of Blepharis edulis (Forssk.) Pers., family Acanthaceae; two new diacyl flavone derivatives: apigenin-7-O-(2″-acetyl-6″-E-p-coumaroyl-β-d-glucopyranoside) (1) and apigenin-7-O-(4″-acetyl-6″-E-p-coumaroyl-β-d-glucopyranoside) (2), along with eight known compounds: apigenin-7-O-(3″-acetyl-6″-E-p-coumaroyl-β-d-glucopyranoside) (3), naringenin-7-O-(3″-acetyl-6″-E-p-coumaroyl-β-d-glucopyranoside) (4), apigenin-7-O-(6″-E-p-coumaroyl-β-d-glucopyranoside) (5), naringenin-7-O-(6″-E-p-coumaroyl-β-d-glucopyranoside) (6), acacetin (7), naringenin (8), vanillic acid (9) and 4-hydroxybenzoic acid (10) were isolated and unambiguously identified from the ether fraction of the total extract of the wild Egyptian species B. edulis (Forssk.), family Acanthaceae. Identification and structure elucidation of the isolated compounds were carried out and confirmed through full data obtained from different 1D and 2D NMR experiments and mass spectral analyses. Compounds 1–9 were isolated for the first time from the species. Compounds 1 and 2 are new natural products isolated herein for the first time in nature.http://www.sciencedirect.com/science/article/pii/S1110093115000046Blepharis edulisDiacyl flavonoid derivativesAcylated apigenin glucosidesAcylated naringenin glucosides |
| spellingShingle | Mohamed Abdel-Ghaffar Ashour New diacyl flavonoid derivatives from the Egyptian plant Blepharis edulis (Forssk.) Pers. Bulletin of Faculty of Pharmacy Cairo University Blepharis edulis Diacyl flavonoid derivatives Acylated apigenin glucosides Acylated naringenin glucosides |
| title | New diacyl flavonoid derivatives from the Egyptian plant Blepharis edulis (Forssk.) Pers. |
| title_full | New diacyl flavonoid derivatives from the Egyptian plant Blepharis edulis (Forssk.) Pers. |
| title_fullStr | New diacyl flavonoid derivatives from the Egyptian plant Blepharis edulis (Forssk.) Pers. |
| title_full_unstemmed | New diacyl flavonoid derivatives from the Egyptian plant Blepharis edulis (Forssk.) Pers. |
| title_short | New diacyl flavonoid derivatives from the Egyptian plant Blepharis edulis (Forssk.) Pers. |
| title_sort | new diacyl flavonoid derivatives from the egyptian plant blepharis edulis forssk pers |
| topic | Blepharis edulis Diacyl flavonoid derivatives Acylated apigenin glucosides Acylated naringenin glucosides |
| url | http://www.sciencedirect.com/science/article/pii/S1110093115000046 |
| work_keys_str_mv | AT mohamedabdelghaffarashour newdiacylflavonoidderivativesfromtheegyptianplantblepharisedulisforsskpers |