Sirtuin 1 and Sirtuin 3 in Granulosa Cell Tumors

Sirtuin 1 and Sirtuin 3 in Granulosa Cell Tumors

Sirtuins (SIRTs) are NAD<sup>+</sup>-dependent deacetylases that regulate proliferation and cell death. In the human ovary, granulosa cells express sirtuin 1 (SIRT1), which has also been detected in human tumors derived from granulosa cells, i.e., granulosa cell tumors (GCTs), and in KGN...

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Bibliographic Details
Main Authors: Nina Schmid, Kim-Gwendolyn Dietrich, Ignasi Forne, Alexander Burges, Magdalena Szymanska, Rina Meidan, Doris Mayr, Artur Mayerhofer
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
granulosa cell tumor
KGN
sirtuin 1
sirtuin 3
siRNA silencing
EX 527
Online Access:https://www.mdpi.com/1422-0067/22/4/2047

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