IgG4-Related Disease With Gastrointestinal Involvement: Case Reports and Literature Review

IgG4-related disease is an immune-mediated chronic, systemic, and autoinflammatory disease that can affect various organs throughout the body. The most commonly affected areas are the pancreas and biliary system. Due to the diverse clinical manifestations of the disease, it affects widely distribute...

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Main Authors: Xinhe Zhang, Xing Jin, Lin Guan, Xuyong Lin, Xuedan Li, Yiling Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.816830/full
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author Xinhe Zhang
Xing Jin
Lin Guan
Xuyong Lin
Xuedan Li
Yiling Li
author_facet Xinhe Zhang
Xing Jin
Lin Guan
Xuyong Lin
Xuedan Li
Yiling Li
author_sort Xinhe Zhang
collection DOAJ
description IgG4-related disease is an immune-mediated chronic, systemic, and autoinflammatory disease that can affect various organs throughout the body. The most commonly affected areas are the pancreas and biliary system. Due to the diverse clinical manifestations of the disease, it affects widely distributed organs. Thus, it is often easy to misdiagnose or miss. The digestive tract is a rarely affected system, and most IgG4-related gastric diseases manifest as tumors detected by endoscopy. This article reports two special cases with IgG4-related disease involving atrophic gastritis and intestinal polyps to provide a more empirical and theoretical basis for clinical diagnosis and treatment.
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spelling doaj.art-893243625da248dfb7d7e5aed0c8669f2022-12-21T18:42:26ZengFrontiers Media S.A.Frontiers in Immunology1664-32242022-03-011310.3389/fimmu.2022.816830816830IgG4-Related Disease With Gastrointestinal Involvement: Case Reports and Literature ReviewXinhe Zhang0Xing Jin1Lin Guan2Xuyong Lin3Xuedan Li4Yiling Li5Gastroenterology Department, The First Affiliated Hospital of China Medical University, Shenyang, ChinaGastroenterology Department, The First Affiliated Hospital of China Medical University, Shenyang, ChinaGastroenterology Department, The First Affiliated Hospital of China Medical University, Shenyang, ChinaDepartment of Pathology, The First Affiliated Hospital of China Medical University, Shenyang, ChinaRadiology Department, The First Affiliated Hospital of China Medical University, Shenyang, ChinaGastroenterology Department, The First Affiliated Hospital of China Medical University, Shenyang, ChinaIgG4-related disease is an immune-mediated chronic, systemic, and autoinflammatory disease that can affect various organs throughout the body. The most commonly affected areas are the pancreas and biliary system. Due to the diverse clinical manifestations of the disease, it affects widely distributed organs. Thus, it is often easy to misdiagnose or miss. The digestive tract is a rarely affected system, and most IgG4-related gastric diseases manifest as tumors detected by endoscopy. This article reports two special cases with IgG4-related disease involving atrophic gastritis and intestinal polyps to provide a more empirical and theoretical basis for clinical diagnosis and treatment.https://www.frontiersin.org/articles/10.3389/fimmu.2022.816830/fullIgG4-related diseaseIgG4-related gastric diseaseIgG4-related sclerosing cholangitisatrophic gastritisautoimmune diseases
spellingShingle Xinhe Zhang
Xing Jin
Lin Guan
Xuyong Lin
Xuedan Li
Yiling Li
IgG4-Related Disease With Gastrointestinal Involvement: Case Reports and Literature Review
Frontiers in Immunology
IgG4-related disease
IgG4-related gastric disease
IgG4-related sclerosing cholangitis
atrophic gastritis
autoimmune diseases
title IgG4-Related Disease With Gastrointestinal Involvement: Case Reports and Literature Review
title_full IgG4-Related Disease With Gastrointestinal Involvement: Case Reports and Literature Review
title_fullStr IgG4-Related Disease With Gastrointestinal Involvement: Case Reports and Literature Review
title_full_unstemmed IgG4-Related Disease With Gastrointestinal Involvement: Case Reports and Literature Review
title_short IgG4-Related Disease With Gastrointestinal Involvement: Case Reports and Literature Review
title_sort igg4 related disease with gastrointestinal involvement case reports and literature review
topic IgG4-related disease
IgG4-related gastric disease
IgG4-related sclerosing cholangitis
atrophic gastritis
autoimmune diseases
url https://www.frontiersin.org/articles/10.3389/fimmu.2022.816830/full
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