Trends in Childhood Thyroid Cancer incidence in Korea and Its Potential Risk Factors
BackgroundAlthough the incidence of thyroid cancer had been increasing until a few years ago, a decrease has been observed in the last years, probably due to the reduction of the screening tests in Korea. Childhood thyroid cancer has been increasing in the past with the same trend as in adults, but...
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| Format: | Article |
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Frontiers Media S.A.
2021-05-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2021.681148/full |
| _version_ | 1818640794121142272 |
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| author | Jun Park Jun Park Hyunju Park Tae Hyuk Kim Sun Wook Kim Hye Won Jang Jae Hoon Chung |
| author_facet | Jun Park Jun Park Hyunju Park Tae Hyuk Kim Sun Wook Kim Hye Won Jang Jae Hoon Chung |
| author_sort | Jun Park |
| collection | DOAJ |
| description | BackgroundAlthough the incidence of thyroid cancer had been increasing until a few years ago, a decrease has been observed in the last years, probably due to the reduction of the screening tests in Korea. Childhood thyroid cancer has been increasing in the past with the same trend as in adults, but there have been few reports on recent trends. We analyzed the trends of thyroid cancer in Korean children and related factors.MethodsFrom national statistics and cancer register database, the data of age-specific incidence rate in Korean childhood thyroid cancer from 1999 to 2017 was obtained, and levels of seaweed intake, the number of computed tomography (CT) and neck ultrasonography (US), obesity prevalence rate, and smoking and alcohol consumption rates in children were analyzed.ResultsThe age-specific incidence of thyroid cancer in Korean children has increased in both genders between 1999 and 2017 (2.0 in 1999 vs. 7.2 in 2017, per population of 100,000), especially in the age group of 14-18 years (1.5 in 1999 vs. 5.5 in 2017, per population of 100,000). During the same period, levels of seaweed intake, number of CT scans and neck US, and prevalence of obesity in children increased significantly, while childhood smoking and alcohol consumption rates decreased.ConclusionUnlike the adult thyroid cancer in Korea, childhood thyroid cancer continues to increase, and the cause might be accompanied by actual increases due to the environmental factors such as excessive iodine intake, exposure to medical radiation, and increased obesity prevalence as well as the screening effect. |
| first_indexed | 2024-12-16T23:16:56Z |
| format | Article |
| id | doaj.art-89366a2a17924f6f9ddbe1b17e6f0205 |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-12-16T23:16:56Z |
| publishDate | 2021-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-89366a2a17924f6f9ddbe1b17e6f02052022-12-21T22:12:16ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922021-05-011210.3389/fendo.2021.681148681148Trends in Childhood Thyroid Cancer incidence in Korea and Its Potential Risk FactorsJun Park0Jun Park1Hyunju Park2Tae Hyuk Kim3Sun Wook Kim4Hye Won Jang5Jae Hoon Chung6Division of Endocrinology and Metabolism, Department of Medicine, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South KoreaDivision of Endocrinology, Department of Medicine, Sahmyook Medical Center, Seoul, South KoreaDivision of Endocrinology and Metabolism, Department of Medicine, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South KoreaDivision of Endocrinology and Metabolism, Department of Medicine, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South KoreaDivision of Endocrinology and Metabolism, Department of Medicine, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South KoreaDepartment of Medical Education, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South KoreaDivision of Endocrinology and Metabolism, Department of Medicine, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South KoreaBackgroundAlthough the incidence of thyroid cancer had been increasing until a few years ago, a decrease has been observed in the last years, probably due to the reduction of the screening tests in Korea. Childhood thyroid cancer has been increasing in the past with the same trend as in adults, but there have been few reports on recent trends. We analyzed the trends of thyroid cancer in Korean children and related factors.MethodsFrom national statistics and cancer register database, the data of age-specific incidence rate in Korean childhood thyroid cancer from 1999 to 2017 was obtained, and levels of seaweed intake, the number of computed tomography (CT) and neck ultrasonography (US), obesity prevalence rate, and smoking and alcohol consumption rates in children were analyzed.ResultsThe age-specific incidence of thyroid cancer in Korean children has increased in both genders between 1999 and 2017 (2.0 in 1999 vs. 7.2 in 2017, per population of 100,000), especially in the age group of 14-18 years (1.5 in 1999 vs. 5.5 in 2017, per population of 100,000). During the same period, levels of seaweed intake, number of CT scans and neck US, and prevalence of obesity in children increased significantly, while childhood smoking and alcohol consumption rates decreased.ConclusionUnlike the adult thyroid cancer in Korea, childhood thyroid cancer continues to increase, and the cause might be accompanied by actual increases due to the environmental factors such as excessive iodine intake, exposure to medical radiation, and increased obesity prevalence as well as the screening effect.https://www.frontiersin.org/articles/10.3389/fendo.2021.681148/fullchildhoodthyroidcancerincidenceincreaseKorea |
| spellingShingle | Jun Park Jun Park Hyunju Park Tae Hyuk Kim Sun Wook Kim Hye Won Jang Jae Hoon Chung Trends in Childhood Thyroid Cancer incidence in Korea and Its Potential Risk Factors Frontiers in Endocrinology childhood thyroid cancer incidence increase Korea |
| title | Trends in Childhood Thyroid Cancer incidence in Korea and Its Potential Risk Factors |
| title_full | Trends in Childhood Thyroid Cancer incidence in Korea and Its Potential Risk Factors |
| title_fullStr | Trends in Childhood Thyroid Cancer incidence in Korea and Its Potential Risk Factors |
| title_full_unstemmed | Trends in Childhood Thyroid Cancer incidence in Korea and Its Potential Risk Factors |
| title_short | Trends in Childhood Thyroid Cancer incidence in Korea and Its Potential Risk Factors |
| title_sort | trends in childhood thyroid cancer incidence in korea and its potential risk factors |
| topic | childhood thyroid cancer incidence increase Korea |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2021.681148/full |
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