Improving cancer immunotherapy via co-delivering checkpoint blockade and thrombospondin-1 downregulator

The use of checkpoint-blockade antibodies is still restricted in several malignancies due to the modest efficacy, despite considerable success in anti-tumor immunotherapy. The poor response of cancer cells to immune destruction is an essential contributor to the failure of checkpoint therapy. We hyp...

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Bibliographic Details
Main Authors: Qingqing Xiao, Xiaotong Li, Chang Liu, Yuxin Jiang, Yonglong He, Wanting Zhang, Helena S. Azevedo, Wei Wu, Yuanzheng Xia, Wei He
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383522003240