The effect of Ramadan fasting on non-alcoholic fatty liver disease (NAFLD) patients: a prospective observational study
Purpose: The aim of this study was to compare biochemical tests, body composition and anthropometric parameters in Nonalcoholic Fatty Liver Disease (NAFLD) patients before and after Ramadan fasting. Methods: fifty NAFLD patients including 33 males and 17 females aged 18-65 year, were recruited. Subj...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2015-07-01
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| Series: | Journal of Fasting and Health |
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| Online Access: | http://jfh.mums.ac.ir/pdf_4621_c182bfcd3ed1828b00ceb43198d28ba7.html |
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| author | Seyed Mostafa Arabi Sudiyeh Hejri Zarifi Mohsen Nematy Mohammad Safarian |
| author_facet | Seyed Mostafa Arabi Sudiyeh Hejri Zarifi Mohsen Nematy Mohammad Safarian |
| author_sort | Seyed Mostafa Arabi |
| collection | DOAJ |
| description | Purpose: The aim of this study was to compare biochemical tests, body composition and anthropometric parameters in Nonalcoholic Fatty Liver Disease (NAFLD) patients before and after Ramadan fasting. Methods: fifty NAFLD patients including 33 males and 17 females aged 18-65 year, were recruited. Subjects attended after diagnosis based on ultrasound imaging, with at least 10 hour fasting, before and after Ramadan who were been fasting for at least 10 days. A fasting blood sample was obtained, blood pressure was measured and body mass index(BMI) and fat mass (FM) and fat free mass (FFM) were calculated. Lipid profile, fasting blood sugar (FBS),insulin, ALT and AST enzymes were analyzed on all blood samples. Result: There was a significant increase in HDL-c in females and higher total plasma cholesterol, triglyceride (TG) and FBS in both gender while lower systolic blood pressure (SBP), diastolic blood pressure (DBP) and ALT decreasing after Ramadan (P0.05, t test). Conclusion: This study shows significant effects on NAFLD patient parameters during Ramadan fasting such as decreasing in insulin, ALT enzyme, SBP and DBP and increasing in HDL-c after an average of 27 d fasting, Result from this study suggested that Ramadan fasting may be useful to improve NAFLD, so further studies are needed in this area. |
| first_indexed | 2024-12-16T14:54:09Z |
| format | Article |
| id | doaj.art-893839931f834421b2143e82c3014422 |
| institution | Directory Open Access Journal |
| issn | 2345-2587 2345-2587 |
| language | English |
| last_indexed | 2024-12-16T14:54:09Z |
| publishDate | 2015-07-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Journal of Fasting and Health |
| spelling | doaj.art-893839931f834421b2143e82c30144222022-12-21T22:27:30ZengMashhad University of Medical SciencesJournal of Fasting and Health2345-25872345-25872015-07-013274804621The effect of Ramadan fasting on non-alcoholic fatty liver disease (NAFLD) patients: a prospective observational studySeyed Mostafa Arabi0Sudiyeh Hejri Zarifi1Mohsen Nematy2Mohammad Safarian3Department of Biochemistry and Nutrition Sciences. Mashhad University of Medical Sciences. Mashhad, IranDepartment of Biochemistry and Nutrition Sciences. Mashhad University of Medical Sciences. Mashhad, IranDepartment of Biochemistry and Nutrition Sciences. Mashhad University of Medical Sciences. Mashhad, IranDepartment of Biochemistry and Nutrition Sciences. Mashhad University of Medical Sciences. Mashhad, IranPurpose: The aim of this study was to compare biochemical tests, body composition and anthropometric parameters in Nonalcoholic Fatty Liver Disease (NAFLD) patients before and after Ramadan fasting. Methods: fifty NAFLD patients including 33 males and 17 females aged 18-65 year, were recruited. Subjects attended after diagnosis based on ultrasound imaging, with at least 10 hour fasting, before and after Ramadan who were been fasting for at least 10 days. A fasting blood sample was obtained, blood pressure was measured and body mass index(BMI) and fat mass (FM) and fat free mass (FFM) were calculated. Lipid profile, fasting blood sugar (FBS),insulin, ALT and AST enzymes were analyzed on all blood samples. Result: There was a significant increase in HDL-c in females and higher total plasma cholesterol, triglyceride (TG) and FBS in both gender while lower systolic blood pressure (SBP), diastolic blood pressure (DBP) and ALT decreasing after Ramadan (P0.05, t test). Conclusion: This study shows significant effects on NAFLD patient parameters during Ramadan fasting such as decreasing in insulin, ALT enzyme, SBP and DBP and increasing in HDL-c after an average of 27 d fasting, Result from this study suggested that Ramadan fasting may be useful to improve NAFLD, so further studies are needed in this area.http://jfh.mums.ac.ir/pdf_4621_c182bfcd3ed1828b00ceb43198d28ba7.htmlnonalcoholic fatty liver diseaseRamadanFastingALTInsulin |
| spellingShingle | Seyed Mostafa Arabi Sudiyeh Hejri Zarifi Mohsen Nematy Mohammad Safarian The effect of Ramadan fasting on non-alcoholic fatty liver disease (NAFLD) patients: a prospective observational study Journal of Fasting and Health nonalcoholic fatty liver disease Ramadan Fasting ALT Insulin |
| title | The effect of Ramadan fasting on non-alcoholic fatty liver disease (NAFLD) patients: a prospective observational study |
| title_full | The effect of Ramadan fasting on non-alcoholic fatty liver disease (NAFLD) patients: a prospective observational study |
| title_fullStr | The effect of Ramadan fasting on non-alcoholic fatty liver disease (NAFLD) patients: a prospective observational study |
| title_full_unstemmed | The effect of Ramadan fasting on non-alcoholic fatty liver disease (NAFLD) patients: a prospective observational study |
| title_short | The effect of Ramadan fasting on non-alcoholic fatty liver disease (NAFLD) patients: a prospective observational study |
| title_sort | effect of ramadan fasting on non alcoholic fatty liver disease nafld patients a prospective observational study |
| topic | nonalcoholic fatty liver disease Ramadan Fasting ALT Insulin |
| url | http://jfh.mums.ac.ir/pdf_4621_c182bfcd3ed1828b00ceb43198d28ba7.html |
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