Endothelium-related Cardiovascular Risk Factors in Subclinical Hypothyroidism
The aim of the study was to evaluate the endothelial function in patients with subclinical hypothyroidism. 39 patients and a control group of 14 matched persons group were included in cross-sectional research. In subclinical hypothyroid patients endothelium-dependent vasodilatation significantly dec...
| Format: | Article |
|---|---|
| Language: | Russian |
| Published: |
Endocrinology Research Centre
2009-03-01
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| Series: | Клиническая и экспериментальная тиреоидология |
| Subjects: | |
| Online Access: | https://cet-endojournals.ru/ket/article/viewFile/4485/2612 |
| _version_ | 1818647162761773056 |
|---|---|
| collection | DOAJ |
| description | The aim of the study was to evaluate the endothelial function in patients with subclinical hypothyroidism. 39 patients and a control group of 14 matched persons group were included in cross-sectional research. In subclinical hypothyroid patients endothelium-dependent vasodilatation significantly decreased, while endothelin-1 and PAI-1 levels increased. Levels of total cholesterol and low-density lipoproteins were significantly higher in patients with subclinical hypothyroidism than in control group, and their positive correlation with TSH was revealed. These findings allow us to make a conclusion on presence of endothelial dysfunction and atherogenic dislipoproteinemia in patients with subclinical hypothyroidism. |
| first_indexed | 2024-12-17T00:58:09Z |
| format | Article |
| id | doaj.art-8938fc17bf13498f8fbd538d8413844c |
| institution | Directory Open Access Journal |
| issn | 1995-5472 2310-3787 |
| language | Russian |
| last_indexed | 2024-12-17T00:58:09Z |
| publishDate | 2009-03-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Клиническая и экспериментальная тиреоидология |
| spelling | doaj.art-8938fc17bf13498f8fbd538d8413844c2022-12-21T22:09:33ZrusEndocrinology Research CentreКлиническая и экспериментальная тиреоидология1995-54722310-37872009-03-0151262910.14341/ket20095126-294443Endothelium-related Cardiovascular Risk Factors in Subclinical HypothyroidismThe aim of the study was to evaluate the endothelial function in patients with subclinical hypothyroidism. 39 patients and a control group of 14 matched persons group were included in cross-sectional research. In subclinical hypothyroid patients endothelium-dependent vasodilatation significantly decreased, while endothelin-1 and PAI-1 levels increased. Levels of total cholesterol and low-density lipoproteins were significantly higher in patients with subclinical hypothyroidism than in control group, and their positive correlation with TSH was revealed. These findings allow us to make a conclusion on presence of endothelial dysfunction and atherogenic dislipoproteinemia in patients with subclinical hypothyroidism.https://cet-endojournals.ru/ket/article/viewFile/4485/2612subclinical hypothyroidismendothelial dysfunctioncardiovascular risk |
| spellingShingle | Endothelium-related Cardiovascular Risk Factors in Subclinical Hypothyroidism Клиническая и экспериментальная тиреоидология subclinical hypothyroidism endothelial dysfunction cardiovascular risk |
| title | Endothelium-related Cardiovascular Risk Factors in Subclinical Hypothyroidism |
| title_full | Endothelium-related Cardiovascular Risk Factors in Subclinical Hypothyroidism |
| title_fullStr | Endothelium-related Cardiovascular Risk Factors in Subclinical Hypothyroidism |
| title_full_unstemmed | Endothelium-related Cardiovascular Risk Factors in Subclinical Hypothyroidism |
| title_short | Endothelium-related Cardiovascular Risk Factors in Subclinical Hypothyroidism |
| title_sort | endothelium related cardiovascular risk factors in subclinical hypothyroidism |
| topic | subclinical hypothyroidism endothelial dysfunction cardiovascular risk |
| url | https://cet-endojournals.ru/ket/article/viewFile/4485/2612 |