How to recognize a trustworthy clinical practice guideline

Abstract Trustworthy clinical practice guidelines represent a fundamental tool to summarize relevant evidence regarding a set of clinical choices and provide guidance for making optimal clinical decisions. Clinicians must differentiate between guidelines that provide trustworthy evidence guidance an...

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Main Authors: João Pedro Lima, Reza D. Mirza, Gordon H. Guyatt
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Journal of Anesthesia, Analgesia and Critical Care
Subjects:
Online Access:https://doi.org/10.1186/s44158-023-00094-7
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author João Pedro Lima
Reza D. Mirza
Gordon H. Guyatt
author_facet João Pedro Lima
Reza D. Mirza
Gordon H. Guyatt
author_sort João Pedro Lima
collection DOAJ
description Abstract Trustworthy clinical practice guidelines represent a fundamental tool to summarize relevant evidence regarding a set of clinical choices and provide guidance for making optimal clinical decisions. Clinicians must differentiate between guidelines that provide trustworthy evidence guidance and those that do not. We present six questions clinicians should ask when evaluating a guideline’s trustworthiness. (1) Are the recommendations clear?; (2) Have the panelists considered all alternatives?; (3) Have the panelists considered all patient-important outcomes?; (4) Is the recommendation based on an up-to-date systematic review?; (5) Is the strength of the recommendation compatible with the certainty of the evidence?; (6) Might conflicts of interest influence the recommendations? If yes, were they managed? Once the conclude they are dealing with a trustworthy guideline, clinicians must gain an understanding of the transparent evidence summary that the guideline will offer, and judge the applicability of trustworthy recommendations to their patients and settings. Consideration of the circumstances and values and preferences of patients will be crucial for all weak or conditional recommendations.
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spelling doaj.art-893b56960f1b4deaa327047d5538328c2023-04-30T11:31:33ZengBMCJournal of Anesthesia, Analgesia and Critical Care2731-37862023-04-01311710.1186/s44158-023-00094-7How to recognize a trustworthy clinical practice guidelineJoão Pedro Lima0Reza D. Mirza1Gordon H. Guyatt2Department of Health Research Methods, Evidence, and Impact, McMaster UniversityDepartment of Health Research Methods, Evidence, and Impact, McMaster UniversityDepartment of Health Research Methods, Evidence, and Impact, McMaster UniversityAbstract Trustworthy clinical practice guidelines represent a fundamental tool to summarize relevant evidence regarding a set of clinical choices and provide guidance for making optimal clinical decisions. Clinicians must differentiate between guidelines that provide trustworthy evidence guidance and those that do not. We present six questions clinicians should ask when evaluating a guideline’s trustworthiness. (1) Are the recommendations clear?; (2) Have the panelists considered all alternatives?; (3) Have the panelists considered all patient-important outcomes?; (4) Is the recommendation based on an up-to-date systematic review?; (5) Is the strength of the recommendation compatible with the certainty of the evidence?; (6) Might conflicts of interest influence the recommendations? If yes, were they managed? Once the conclude they are dealing with a trustworthy guideline, clinicians must gain an understanding of the transparent evidence summary that the guideline will offer, and judge the applicability of trustworthy recommendations to their patients and settings. Consideration of the circumstances and values and preferences of patients will be crucial for all weak or conditional recommendations.https://doi.org/10.1186/s44158-023-00094-7Clinical practice guidelinesGRADE approachEvidence-based medicineRecommendation
spellingShingle João Pedro Lima
Reza D. Mirza
Gordon H. Guyatt
How to recognize a trustworthy clinical practice guideline
Journal of Anesthesia, Analgesia and Critical Care
Clinical practice guidelines
GRADE approach
Evidence-based medicine
Recommendation
title How to recognize a trustworthy clinical practice guideline
title_full How to recognize a trustworthy clinical practice guideline
title_fullStr How to recognize a trustworthy clinical practice guideline
title_full_unstemmed How to recognize a trustworthy clinical practice guideline
title_short How to recognize a trustworthy clinical practice guideline
title_sort how to recognize a trustworthy clinical practice guideline
topic Clinical practice guidelines
GRADE approach
Evidence-based medicine
Recommendation
url https://doi.org/10.1186/s44158-023-00094-7
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