A comparative study assessing the efficacy and safety of radiofrequency ablation versus surgical treatment for osteoid osteoma: retrospective analysis in a single institution
Abstract Objective We aim to evaluate the efficacy of CT-guided percutaneous radiofrequency ablation (RFA) and surgical treatment in osteoid osteoma (OO) treated at the Medical University of Graz. Materials and methods In a single-institution study, we analysed data from January 2005 to January 2021...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2024-03-01
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| Series: | Insights into Imaging |
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| Online Access: | https://doi.org/10.1186/s13244-024-01656-1 |
| _version_ | 1797247210969104384 |
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| author | Jasminka Igrec Maria Anna Smolle Michael Meszarics Theresa Marie Godschachner Jakob Steiner Mira Feichtinger Emina Talakic Rupert Horst Portugaller Andreas Leithner Michael Fuchsjäger Iva Brcic |
| author_facet | Jasminka Igrec Maria Anna Smolle Michael Meszarics Theresa Marie Godschachner Jakob Steiner Mira Feichtinger Emina Talakic Rupert Horst Portugaller Andreas Leithner Michael Fuchsjäger Iva Brcic |
| author_sort | Jasminka Igrec |
| collection | DOAJ |
| description | Abstract Objective We aim to evaluate the efficacy of CT-guided percutaneous radiofrequency ablation (RFA) and surgical treatment in osteoid osteoma (OO) treated at the Medical University of Graz. Materials and methods In a single-institution study, we analysed data from January 2005 to January 2021 of patients with histological/radiological diagnosis of OO. CT and MRI scans were reviewed for typical findings. Means (with SD) and medians (with IQR) were reported for normally and non-normally distributed variables. Differences between groups were assessed using chi-squared tests and t-tests. Results One hundred nineteen patients (mean age: 21.6 ± 10.9 years; 63.9% males) with confirmed OO were retrospectively evaluated. 73 and 43 patients underwent RFA and surgery, respectively. In three cases, RFA combined with surgery was performed. Pre-intervention, 103 patients (88.8%) had undergone CT, and 101 had an MRI (87.1%). The nidus was confirmed in 82.5% of cases with CTs (85/103) and 63.4% with MRIs (64/101). The majority of nidi were located cortically (n = 96; 82.8%), most frequently in the femur (38 patients, 33.3%) with a median size of 8.0 mm (IQR: 5.0–12.0 mm). Median symptom duration before treatment was 6.0 (IQR: 4.0–13.0) months. The complication rate was 12.1% (14/116; 15.1% RFA vs. 7.0% surgery; p = 0.196). In total, 11.2% of patients had persistent symptoms after one week with clinical success rates of RFA and surgery, 86.3% and 90.7% (p = 0.647), respectively. Conclusion Compared to surgical treatment, CT-guided percutaneous RFA is a safe, minimally invasive, reliable, and efficient treatment option for OO. Critical relevance statement This article critically assesses the diagnosis and treatment of osteoid osteoma, emphasising accurate imaging, and detailing a non-invasive option for effective management. Key points • This study analyses 116 cases of OO at one institution, focusing on symptom persistence, recurrence in short-term follow-up, and complications in two study groups. • Surgery showed higher, though not statistically significant, success despite comparable symptom persistence; CT displayed typical OO features more than MRI, regardless of the intramedullary, cortical and subperiosteal location as well as the site of the affected bone. • CT-guided RFA is an effective therapeutic alternative for OO compared to surgical intervention. In case of atypical OO appearance, RFA is not the first-line treatment. Graphical Abstract |
| first_indexed | 2024-04-24T19:55:05Z |
| format | Article |
| id | doaj.art-893bf576aba346c9900d01aebcce4e85 |
| institution | Directory Open Access Journal |
| issn | 1869-4101 |
| language | English |
| last_indexed | 2024-04-24T19:55:05Z |
| publishDate | 2024-03-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Insights into Imaging |
| spelling | doaj.art-893bf576aba346c9900d01aebcce4e852024-03-24T12:23:00ZengSpringerOpenInsights into Imaging1869-41012024-03-0115111010.1186/s13244-024-01656-1A comparative study assessing the efficacy and safety of radiofrequency ablation versus surgical treatment for osteoid osteoma: retrospective analysis in a single institutionJasminka Igrec0Maria Anna Smolle1Michael Meszarics2Theresa Marie Godschachner3Jakob Steiner4Mira Feichtinger5Emina Talakic6Rupert Horst Portugaller7Andreas Leithner8Michael Fuchsjäger9Iva Brcic10Division of General Radiology, Department of Radiology, Medical University of GrazDepartment of Orthopaedics and Traumatology, Medical University of GrazDiagnostic and Research Institute of Pathology, Medical University of GrazDiagnostic and Research Institute of Pathology, Medical University of GrazDivision of General Radiology, Department of Radiology, Medical University of GrazDivision of General Radiology, Department of Radiology, Medical University of GrazDivision of General Radiology, Department of Radiology, Medical University of GrazDivision of Neuroradiology, Vascular and Interventional Radiology, Department of Radiology, Medical University of GrazDepartment of Orthopaedics and Traumatology, Medical University of GrazDivision of General Radiology, Department of Radiology, Medical University of GrazDiagnostic and Research Institute of Pathology, Medical University of GrazAbstract Objective We aim to evaluate the efficacy of CT-guided percutaneous radiofrequency ablation (RFA) and surgical treatment in osteoid osteoma (OO) treated at the Medical University of Graz. Materials and methods In a single-institution study, we analysed data from January 2005 to January 2021 of patients with histological/radiological diagnosis of OO. CT and MRI scans were reviewed for typical findings. Means (with SD) and medians (with IQR) were reported for normally and non-normally distributed variables. Differences between groups were assessed using chi-squared tests and t-tests. Results One hundred nineteen patients (mean age: 21.6 ± 10.9 years; 63.9% males) with confirmed OO were retrospectively evaluated. 73 and 43 patients underwent RFA and surgery, respectively. In three cases, RFA combined with surgery was performed. Pre-intervention, 103 patients (88.8%) had undergone CT, and 101 had an MRI (87.1%). The nidus was confirmed in 82.5% of cases with CTs (85/103) and 63.4% with MRIs (64/101). The majority of nidi were located cortically (n = 96; 82.8%), most frequently in the femur (38 patients, 33.3%) with a median size of 8.0 mm (IQR: 5.0–12.0 mm). Median symptom duration before treatment was 6.0 (IQR: 4.0–13.0) months. The complication rate was 12.1% (14/116; 15.1% RFA vs. 7.0% surgery; p = 0.196). In total, 11.2% of patients had persistent symptoms after one week with clinical success rates of RFA and surgery, 86.3% and 90.7% (p = 0.647), respectively. Conclusion Compared to surgical treatment, CT-guided percutaneous RFA is a safe, minimally invasive, reliable, and efficient treatment option for OO. Critical relevance statement This article critically assesses the diagnosis and treatment of osteoid osteoma, emphasising accurate imaging, and detailing a non-invasive option for effective management. Key points • This study analyses 116 cases of OO at one institution, focusing on symptom persistence, recurrence in short-term follow-up, and complications in two study groups. • Surgery showed higher, though not statistically significant, success despite comparable symptom persistence; CT displayed typical OO features more than MRI, regardless of the intramedullary, cortical and subperiosteal location as well as the site of the affected bone. • CT-guided RFA is an effective therapeutic alternative for OO compared to surgical intervention. In case of atypical OO appearance, RFA is not the first-line treatment. Graphical Abstracthttps://doi.org/10.1186/s13244-024-01656-1CTMRIOsteoid osteomaRadiofrequency ablation |
| spellingShingle | Jasminka Igrec Maria Anna Smolle Michael Meszarics Theresa Marie Godschachner Jakob Steiner Mira Feichtinger Emina Talakic Rupert Horst Portugaller Andreas Leithner Michael Fuchsjäger Iva Brcic A comparative study assessing the efficacy and safety of radiofrequency ablation versus surgical treatment for osteoid osteoma: retrospective analysis in a single institution Insights into Imaging CT MRI Osteoid osteoma Radiofrequency ablation |
| title | A comparative study assessing the efficacy and safety of radiofrequency ablation versus surgical treatment for osteoid osteoma: retrospective analysis in a single institution |
| title_full | A comparative study assessing the efficacy and safety of radiofrequency ablation versus surgical treatment for osteoid osteoma: retrospective analysis in a single institution |
| title_fullStr | A comparative study assessing the efficacy and safety of radiofrequency ablation versus surgical treatment for osteoid osteoma: retrospective analysis in a single institution |
| title_full_unstemmed | A comparative study assessing the efficacy and safety of radiofrequency ablation versus surgical treatment for osteoid osteoma: retrospective analysis in a single institution |
| title_short | A comparative study assessing the efficacy and safety of radiofrequency ablation versus surgical treatment for osteoid osteoma: retrospective analysis in a single institution |
| title_sort | comparative study assessing the efficacy and safety of radiofrequency ablation versus surgical treatment for osteoid osteoma retrospective analysis in a single institution |
| topic | CT MRI Osteoid osteoma Radiofrequency ablation |
| url | https://doi.org/10.1186/s13244-024-01656-1 |
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