Mathematical modeling of the Candida albicans yeast to hyphal transition reveals novel control strategies.

Candida albicans, an opportunistic fungal pathogen, is a significant cause of human infections, particularly in immunocompromised individuals. Phenotypic plasticity between two morphological phenotypes, yeast and hyphae, is a key mechanism by which C. albicans can thrive in many microenvironments an...

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Bibliographic Details
Main Authors: David J Wooten, Jorge Gómez Tejeda Zañudo, David Murrugarra, Austin M Perry, Anna Dongari-Bagtzoglou, Reinhard Laubenbacher, Clarissa J Nobile, Réka Albert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008690