Mathematical modeling of the Candida albicans yeast to hyphal transition reveals novel control strategies.
Candida albicans, an opportunistic fungal pathogen, is a significant cause of human infections, particularly in immunocompromised individuals. Phenotypic plasticity between two morphological phenotypes, yeast and hyphae, is a key mechanism by which C. albicans can thrive in many microenvironments an...
Main Authors: | David J Wooten, Jorge Gómez Tejeda Zañudo, David Murrugarra, Austin M Perry, Anna Dongari-Bagtzoglou, Reinhard Laubenbacher, Clarissa J Nobile, Réka Albert |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-03-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1008690 |
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