In Vivo Genotoxicity Evaluation of a Stilbene Extract Prior to Its Use as a Natural Additive: A Combination of the Micronucleus Test and the Comet Assay

In Vivo Genotoxicity Evaluation of a Stilbene Extract Prior to Its Use as a Natural Additive: A Combination of the Micronucleus Test and the Comet Assay

Genotoxic data of substances that could be used as food additives are required by the European Food Safety Authority. In this sense, the use of an extract from grapevine shoots containing a stilbene richness of 99% (ST-99), due to its antioxidant and antibacterial activities, has been proposed as an...

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Bibliographic Details
Main Authors: Concepción Medrano-Padial, María Puerto, Ana Isabel Prieto, Nahúm Ayala, Pauline Beaumont, Caroline Rouger, Stéphanie Krisa, Silvia Pichardo
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Foods
Subjects:
stilbenes
genotoxicity
comet assay
micronucleus
in vivo
rat
Online Access:https://www.mdpi.com/2304-8158/10/2/439

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