EGCG inhibits the inflammation and senescence inducing properties of MDA-MB-231 triple-negative breast cancer (TNBC) cells-derived extracellular vesicles in human adipose-derived mesenchymal stem cells

EGCG inhibits the inflammation and senescence inducing properties of MDA-MB-231 triple-negative breast cancer (TNBC) cells-derived extracellular vesicles in human adipose-derived mesenchymal stem cells

Abstract Background Triple-negative breast cancer (TNBC) cells’ secretome can induce a pro-inflammatory phenotype in human adipose-derived mesenchymal stem cells (hADMSC). This can be prevented by the green tea polyphenol epigallocatechin-3-gallate (EGCG). The impact of EGCG on the paracrine regulat...

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Bibliographic Details
Main Authors: Narjara Gonzalez Suarez, Yuniel Fernandez-Marrero, Mathieu P. A. Hébert, Marie-Eve Roy, Luc H. Boudreau, Borhane Annabi
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Cancer Cell International
Subjects:
EGCG
Triple-negative breast cancer
Extracellular vesicles
Adipose-derived mesenchymal stem cells
Inflammation
Senescence
Online Access:https://doi.org/10.1186/s12935-023-03087-2

Internet

https://doi.org/10.1186/s12935-023-03087-2

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