The regulation of DNA end resection by chromatin response to DNA double strand breaks

The regulation of DNA end resection by chromatin response to DNA double strand breaks

DNA double-strand breaks (DSBs) constantly arise upon exposure to genotoxic agents and during physiological processes. The timely repair of DSBs is important for not only the completion of the cellular functions involving DSBs as intermediates, but also the maintenance of genome stability. There are...

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Bibliographic Details
Main Authors:	Bo-Ruei Chen, Barry P. Sleckman
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-07-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	DNA end resection homologous recombination non-homologous end joining histone modificaitons chromatin remodeling 53BP1
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2022.932633/full

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