Platelet rich fibrin and MTA in the treatment of teeth with open apices

Abstract Background The present study aimed to evaluate the effectiveness of using platelet-rich fibrin (PRF) as the apical matrix for the placement of MTA in nonsurgical endodontic therapy for teeth with periapical lesions and open apices. Methods Twelve teeth from eleven patients with periapical p...

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Main Authors: Van-Khoa Pham, Tran-Lan-Khue Pham, An-Tran Pham, Hoang-Lan-Anh Le, Thi-Bich-Van Tran, Manh-Cuong Hoang, Ta-Binh Vo, Khanh-Ngoc Vy, Minh-Hong Tran, Thi-Anh-Thu Tran, Minh-Anh Bui, Anh-Dung Hoang, Ngoc-Phuc Nguyen, Thi-Tam-Duyen Nguyen, Phuc-Nguyen Nguyen, Thi-Tuong-Vi Tran, Cao-Hoai-Linh Nguyen
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Oral Health
Subjects:
Online Access:https://doi.org/10.1186/s12903-024-03923-5
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author Van-Khoa Pham
Tran-Lan-Khue Pham
An-Tran Pham
Hoang-Lan-Anh Le
Thi-Bich-Van Tran
Manh-Cuong Hoang
Ta-Binh Vo
Khanh-Ngoc Vy
Minh-Hong Tran
Thi-Anh-Thu Tran
Minh-Anh Bui
Anh-Dung Hoang
Ngoc-Phuc Nguyen
Thi-Tam-Duyen Nguyen
Phuc-Nguyen Nguyen
Thi-Tuong-Vi Tran
Cao-Hoai-Linh Nguyen
author_facet Van-Khoa Pham
Tran-Lan-Khue Pham
An-Tran Pham
Hoang-Lan-Anh Le
Thi-Bich-Van Tran
Manh-Cuong Hoang
Ta-Binh Vo
Khanh-Ngoc Vy
Minh-Hong Tran
Thi-Anh-Thu Tran
Minh-Anh Bui
Anh-Dung Hoang
Ngoc-Phuc Nguyen
Thi-Tam-Duyen Nguyen
Phuc-Nguyen Nguyen
Thi-Tuong-Vi Tran
Cao-Hoai-Linh Nguyen
author_sort Van-Khoa Pham
collection DOAJ
description Abstract Background The present study aimed to evaluate the effectiveness of using platelet-rich fibrin (PRF) as the apical matrix for the placement of MTA in nonsurgical endodontic therapy for teeth with periapical lesions and open apices. Methods Twelve teeth from eleven patients with periapical periodontitis and open apices were enrolled in the study. Nonsurgical endodontic therapy was performed with the PRF used as an apical barrier and the MTA manipulated as an apical plug for further thermoplasticized gutta percha in the remaining part of the root canal. Clinical signs and periapical digital radiographs were recorded and analyzed to evaluate the curing progress after periodical follow-ups of 1, 3, and 6 months. The horizontal dimension of the periapical lesion was determined, and the changes in the dimensions were recorded each time. The Friedman test was used for statistical analysis, with P < .05 serving as the threshold for determining statistical significance. Results All patients had no clinical symptoms after the first month of treatment, with a significant reduction in the periapical lesion after periodical appointments. Conclusions PRF is an effective barrier when combined with MTA for the treatment of teeth with periapical periodontitis and open apices.
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spelling doaj.art-8949ffc7a57c455ab103986a9775ab142024-03-10T12:23:29ZengBMCBMC Oral Health1472-68312024-02-012411810.1186/s12903-024-03923-5Platelet rich fibrin and MTA in the treatment of teeth with open apicesVan-Khoa Pham0Tran-Lan-Khue Pham1An-Tran Pham2Hoang-Lan-Anh Le3Thi-Bich-Van Tran4Manh-Cuong Hoang5Ta-Binh Vo6Khanh-Ngoc Vy7Minh-Hong Tran8Thi-Anh-Thu Tran9Minh-Anh Bui10Anh-Dung Hoang11Ngoc-Phuc Nguyen12Thi-Tam-Duyen Nguyen13Phuc-Nguyen Nguyen14Thi-Tuong-Vi Tran15Cao-Hoai-Linh Nguyen16Faculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh CityFaculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh CityFaculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh CityFaculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh CityFaculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh CityFaculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh CityFaculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh CityFaculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh CityNational Hospital of Odonto-StomatologyNational Hospital of Odonto-StomatologyNational Hospital of Odonto-StomatologyNational Hospital of Odonto-StomatologyFaculty of Dentistry, Van Lang UniversityFaculty of Odonto-Stomatology, Tra Vinh UniversityFaculty of Odonto-Stomatology, Tra Vinh UniversityHospital of Odonto-StomatologyHospital of Odonto-StomatologyAbstract Background The present study aimed to evaluate the effectiveness of using platelet-rich fibrin (PRF) as the apical matrix for the placement of MTA in nonsurgical endodontic therapy for teeth with periapical lesions and open apices. Methods Twelve teeth from eleven patients with periapical periodontitis and open apices were enrolled in the study. Nonsurgical endodontic therapy was performed with the PRF used as an apical barrier and the MTA manipulated as an apical plug for further thermoplasticized gutta percha in the remaining part of the root canal. Clinical signs and periapical digital radiographs were recorded and analyzed to evaluate the curing progress after periodical follow-ups of 1, 3, and 6 months. The horizontal dimension of the periapical lesion was determined, and the changes in the dimensions were recorded each time. The Friedman test was used for statistical analysis, with P < .05 serving as the threshold for determining statistical significance. Results All patients had no clinical symptoms after the first month of treatment, with a significant reduction in the periapical lesion after periodical appointments. Conclusions PRF is an effective barrier when combined with MTA for the treatment of teeth with periapical periodontitis and open apices.https://doi.org/10.1186/s12903-024-03923-5PRFMTAApical barrierOpen apexPeriapical periodontitis
spellingShingle Van-Khoa Pham
Tran-Lan-Khue Pham
An-Tran Pham
Hoang-Lan-Anh Le
Thi-Bich-Van Tran
Manh-Cuong Hoang
Ta-Binh Vo
Khanh-Ngoc Vy
Minh-Hong Tran
Thi-Anh-Thu Tran
Minh-Anh Bui
Anh-Dung Hoang
Ngoc-Phuc Nguyen
Thi-Tam-Duyen Nguyen
Phuc-Nguyen Nguyen
Thi-Tuong-Vi Tran
Cao-Hoai-Linh Nguyen
Platelet rich fibrin and MTA in the treatment of teeth with open apices
BMC Oral Health
PRF
MTA
Apical barrier
Open apex
Periapical periodontitis
title Platelet rich fibrin and MTA in the treatment of teeth with open apices
title_full Platelet rich fibrin and MTA in the treatment of teeth with open apices
title_fullStr Platelet rich fibrin and MTA in the treatment of teeth with open apices
title_full_unstemmed Platelet rich fibrin and MTA in the treatment of teeth with open apices
title_short Platelet rich fibrin and MTA in the treatment of teeth with open apices
title_sort platelet rich fibrin and mta in the treatment of teeth with open apices
topic PRF
MTA
Apical barrier
Open apex
Periapical periodontitis
url https://doi.org/10.1186/s12903-024-03923-5
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