Platelet rich fibrin and MTA in the treatment of teeth with open apices
Abstract Background The present study aimed to evaluate the effectiveness of using platelet-rich fibrin (PRF) as the apical matrix for the placement of MTA in nonsurgical endodontic therapy for teeth with periapical lesions and open apices. Methods Twelve teeth from eleven patients with periapical p...
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BMC
2024-02-01
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Series: | BMC Oral Health |
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Online Access: | https://doi.org/10.1186/s12903-024-03923-5 |
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author | Van-Khoa Pham Tran-Lan-Khue Pham An-Tran Pham Hoang-Lan-Anh Le Thi-Bich-Van Tran Manh-Cuong Hoang Ta-Binh Vo Khanh-Ngoc Vy Minh-Hong Tran Thi-Anh-Thu Tran Minh-Anh Bui Anh-Dung Hoang Ngoc-Phuc Nguyen Thi-Tam-Duyen Nguyen Phuc-Nguyen Nguyen Thi-Tuong-Vi Tran Cao-Hoai-Linh Nguyen |
author_facet | Van-Khoa Pham Tran-Lan-Khue Pham An-Tran Pham Hoang-Lan-Anh Le Thi-Bich-Van Tran Manh-Cuong Hoang Ta-Binh Vo Khanh-Ngoc Vy Minh-Hong Tran Thi-Anh-Thu Tran Minh-Anh Bui Anh-Dung Hoang Ngoc-Phuc Nguyen Thi-Tam-Duyen Nguyen Phuc-Nguyen Nguyen Thi-Tuong-Vi Tran Cao-Hoai-Linh Nguyen |
author_sort | Van-Khoa Pham |
collection | DOAJ |
description | Abstract Background The present study aimed to evaluate the effectiveness of using platelet-rich fibrin (PRF) as the apical matrix for the placement of MTA in nonsurgical endodontic therapy for teeth with periapical lesions and open apices. Methods Twelve teeth from eleven patients with periapical periodontitis and open apices were enrolled in the study. Nonsurgical endodontic therapy was performed with the PRF used as an apical barrier and the MTA manipulated as an apical plug for further thermoplasticized gutta percha in the remaining part of the root canal. Clinical signs and periapical digital radiographs were recorded and analyzed to evaluate the curing progress after periodical follow-ups of 1, 3, and 6 months. The horizontal dimension of the periapical lesion was determined, and the changes in the dimensions were recorded each time. The Friedman test was used for statistical analysis, with P < .05 serving as the threshold for determining statistical significance. Results All patients had no clinical symptoms after the first month of treatment, with a significant reduction in the periapical lesion after periodical appointments. Conclusions PRF is an effective barrier when combined with MTA for the treatment of teeth with periapical periodontitis and open apices. |
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format | Article |
id | doaj.art-8949ffc7a57c455ab103986a9775ab14 |
institution | Directory Open Access Journal |
issn | 1472-6831 |
language | English |
last_indexed | 2024-04-25T01:02:53Z |
publishDate | 2024-02-01 |
publisher | BMC |
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series | BMC Oral Health |
spelling | doaj.art-8949ffc7a57c455ab103986a9775ab142024-03-10T12:23:29ZengBMCBMC Oral Health1472-68312024-02-012411810.1186/s12903-024-03923-5Platelet rich fibrin and MTA in the treatment of teeth with open apicesVan-Khoa Pham0Tran-Lan-Khue Pham1An-Tran Pham2Hoang-Lan-Anh Le3Thi-Bich-Van Tran4Manh-Cuong Hoang5Ta-Binh Vo6Khanh-Ngoc Vy7Minh-Hong Tran8Thi-Anh-Thu Tran9Minh-Anh Bui10Anh-Dung Hoang11Ngoc-Phuc Nguyen12Thi-Tam-Duyen Nguyen13Phuc-Nguyen Nguyen14Thi-Tuong-Vi Tran15Cao-Hoai-Linh Nguyen16Faculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh CityFaculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh CityFaculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh CityFaculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh CityFaculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh CityFaculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh CityFaculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh CityFaculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh CityNational Hospital of Odonto-StomatologyNational Hospital of Odonto-StomatologyNational Hospital of Odonto-StomatologyNational Hospital of Odonto-StomatologyFaculty of Dentistry, Van Lang UniversityFaculty of Odonto-Stomatology, Tra Vinh UniversityFaculty of Odonto-Stomatology, Tra Vinh UniversityHospital of Odonto-StomatologyHospital of Odonto-StomatologyAbstract Background The present study aimed to evaluate the effectiveness of using platelet-rich fibrin (PRF) as the apical matrix for the placement of MTA in nonsurgical endodontic therapy for teeth with periapical lesions and open apices. Methods Twelve teeth from eleven patients with periapical periodontitis and open apices were enrolled in the study. Nonsurgical endodontic therapy was performed with the PRF used as an apical barrier and the MTA manipulated as an apical plug for further thermoplasticized gutta percha in the remaining part of the root canal. Clinical signs and periapical digital radiographs were recorded and analyzed to evaluate the curing progress after periodical follow-ups of 1, 3, and 6 months. The horizontal dimension of the periapical lesion was determined, and the changes in the dimensions were recorded each time. The Friedman test was used for statistical analysis, with P < .05 serving as the threshold for determining statistical significance. Results All patients had no clinical symptoms after the first month of treatment, with a significant reduction in the periapical lesion after periodical appointments. Conclusions PRF is an effective barrier when combined with MTA for the treatment of teeth with periapical periodontitis and open apices.https://doi.org/10.1186/s12903-024-03923-5PRFMTAApical barrierOpen apexPeriapical periodontitis |
spellingShingle | Van-Khoa Pham Tran-Lan-Khue Pham An-Tran Pham Hoang-Lan-Anh Le Thi-Bich-Van Tran Manh-Cuong Hoang Ta-Binh Vo Khanh-Ngoc Vy Minh-Hong Tran Thi-Anh-Thu Tran Minh-Anh Bui Anh-Dung Hoang Ngoc-Phuc Nguyen Thi-Tam-Duyen Nguyen Phuc-Nguyen Nguyen Thi-Tuong-Vi Tran Cao-Hoai-Linh Nguyen Platelet rich fibrin and MTA in the treatment of teeth with open apices BMC Oral Health PRF MTA Apical barrier Open apex Periapical periodontitis |
title | Platelet rich fibrin and MTA in the treatment of teeth with open apices |
title_full | Platelet rich fibrin and MTA in the treatment of teeth with open apices |
title_fullStr | Platelet rich fibrin and MTA in the treatment of teeth with open apices |
title_full_unstemmed | Platelet rich fibrin and MTA in the treatment of teeth with open apices |
title_short | Platelet rich fibrin and MTA in the treatment of teeth with open apices |
title_sort | platelet rich fibrin and mta in the treatment of teeth with open apices |
topic | PRF MTA Apical barrier Open apex Periapical periodontitis |
url | https://doi.org/10.1186/s12903-024-03923-5 |
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