Case report: MRI and CT imaging features of a melanocytic tumour affecting a cervical vertebra in an adult dog, and review of differential diagnosis for T1W-hyperintense lesions
A 7-year-old Lhasa Apso presented with a history of left thoracic limb lameness and neck pain. Magnetic resonance imaging revealed a well-defined, extradural lesion that was hyperintense on T1-weighted (T1W) images and isointense on T2-weighted (T2W) images and T2* images located at the left lamina...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-04-01
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| Series: | Frontiers in Veterinary Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2024.1334813/full |
| _version_ | 1797217043786760192 |
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| author | Elli Elizabeth Michaelidou Adriana Kaczmarska Rodrigo Gutierrez-Quintana Joanna Morris Gawain Hammond Ana Cloquell |
| author_facet | Elli Elizabeth Michaelidou Adriana Kaczmarska Rodrigo Gutierrez-Quintana Joanna Morris Gawain Hammond Ana Cloquell |
| author_sort | Elli Elizabeth Michaelidou |
| collection | DOAJ |
| description | A 7-year-old Lhasa Apso presented with a history of left thoracic limb lameness and neck pain. Magnetic resonance imaging revealed a well-defined, extradural lesion that was hyperintense on T1-weighted (T1W) images and isointense on T2-weighted (T2W) images and T2* images located at the left lamina of the C4 vertebra. Computed tomography showed an isoattenuating and contrast-enhancing mass centered on the left C4 vertebral lamina with associated osteolysis. The mass was surgically debulked, and histopathology revealed a malignant melanocytic tumour. The patient recovered completely and received radiotherapy and three doses of the melanoma vaccine as adjunctive treatment. Eighteen months following treatment, the patient presented with neck pain again, but further investigations were declined at this stage, and the patient was euthanised. To the author’s knowledge, this is the first case report describing the imaging characteristics of a cervical extradural melanocytic tumour in a dog. This case illustrates the MRI and CT imaging features and treatment of a canine melanocytic tumour of the cervical vertebrae. |
| first_indexed | 2024-04-24T11:55:35Z |
| format | Article |
| id | doaj.art-894b2672aa6a4fbaa64ffcf76de4b517 |
| institution | Directory Open Access Journal |
| issn | 2297-1769 |
| language | English |
| last_indexed | 2024-04-24T11:55:35Z |
| publishDate | 2024-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj.art-894b2672aa6a4fbaa64ffcf76de4b5172024-04-09T04:53:31ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692024-04-011110.3389/fvets.2024.13348131334813Case report: MRI and CT imaging features of a melanocytic tumour affecting a cervical vertebra in an adult dog, and review of differential diagnosis for T1W-hyperintense lesionsElli Elizabeth MichaelidouAdriana KaczmarskaRodrigo Gutierrez-QuintanaJoanna MorrisGawain HammondAna CloquellA 7-year-old Lhasa Apso presented with a history of left thoracic limb lameness and neck pain. Magnetic resonance imaging revealed a well-defined, extradural lesion that was hyperintense on T1-weighted (T1W) images and isointense on T2-weighted (T2W) images and T2* images located at the left lamina of the C4 vertebra. Computed tomography showed an isoattenuating and contrast-enhancing mass centered on the left C4 vertebral lamina with associated osteolysis. The mass was surgically debulked, and histopathology revealed a malignant melanocytic tumour. The patient recovered completely and received radiotherapy and three doses of the melanoma vaccine as adjunctive treatment. Eighteen months following treatment, the patient presented with neck pain again, but further investigations were declined at this stage, and the patient was euthanised. To the author’s knowledge, this is the first case report describing the imaging characteristics of a cervical extradural melanocytic tumour in a dog. This case illustrates the MRI and CT imaging features and treatment of a canine melanocytic tumour of the cervical vertebrae.https://www.frontiersin.org/articles/10.3389/fvets.2024.1334813/fullmelanocytic neoplasiaMelan-AT1W hyperintensitycervical vertebramelanoma of unknown primarymelanotic schwannoma |
| spellingShingle | Elli Elizabeth Michaelidou Adriana Kaczmarska Rodrigo Gutierrez-Quintana Joanna Morris Gawain Hammond Ana Cloquell Case report: MRI and CT imaging features of a melanocytic tumour affecting a cervical vertebra in an adult dog, and review of differential diagnosis for T1W-hyperintense lesions Frontiers in Veterinary Science melanocytic neoplasia Melan-A T1W hyperintensity cervical vertebra melanoma of unknown primary melanotic schwannoma |
| title | Case report: MRI and CT imaging features of a melanocytic tumour affecting a cervical vertebra in an adult dog, and review of differential diagnosis for T1W-hyperintense lesions |
| title_full | Case report: MRI and CT imaging features of a melanocytic tumour affecting a cervical vertebra in an adult dog, and review of differential diagnosis for T1W-hyperintense lesions |
| title_fullStr | Case report: MRI and CT imaging features of a melanocytic tumour affecting a cervical vertebra in an adult dog, and review of differential diagnosis for T1W-hyperintense lesions |
| title_full_unstemmed | Case report: MRI and CT imaging features of a melanocytic tumour affecting a cervical vertebra in an adult dog, and review of differential diagnosis for T1W-hyperintense lesions |
| title_short | Case report: MRI and CT imaging features of a melanocytic tumour affecting a cervical vertebra in an adult dog, and review of differential diagnosis for T1W-hyperintense lesions |
| title_sort | case report mri and ct imaging features of a melanocytic tumour affecting a cervical vertebra in an adult dog and review of differential diagnosis for t1w hyperintense lesions |
| topic | melanocytic neoplasia Melan-A T1W hyperintensity cervical vertebra melanoma of unknown primary melanotic schwannoma |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2024.1334813/full |
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