In-host population dynamics of Mycobacterium tuberculosis complex during active disease

In-host population dynamics of Mycobacterium tuberculosis complex during active disease

Tuberculosis (TB) is a leading cause of death globally. Understanding the population dynamics of TB’s causative agent Mycobacterium tuberculosis complex (Mtbc) in-host is vital for understanding the efficacy of antibiotic treatment. We use longitudinally collected clinical Mtbc isolates that underwe...

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Bibliographic Details
Main Authors: Roger Vargas, Luca Freschi, Maximillian Marin, L Elaine Epperson, Melissa Smith, Irina Oussenko, David Durbin, Michael Strong, Max Salfinger, Maha Reda Farhat
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-02-01
Series:eLife
Subjects:
genomics
infectious disease
Mycobacterium tuberculosis
sequencing
antibiotic resistance
microbial evolution
Online Access:https://elifesciences.org/articles/61805

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