Pediatric Central Nervous System Tumor Overview and Emerging Treatment Considerations
Pediatric central nervous system (CNS) tumors are the most common solid tumor in children, with the majority being glial in origin. These tumors are classified by the World Health Organization (WHO) as either being low grade (WHO grade 1 and 2) or high grade (WHO grade 3 and 4). Our knowledge of the...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Brain Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3425/13/7/1106 |
| _version_ | 1827733618113380352 |
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| author | Sudarshawn Damodharan Diane Puccetti |
| author_facet | Sudarshawn Damodharan Diane Puccetti |
| author_sort | Sudarshawn Damodharan |
| collection | DOAJ |
| description | Pediatric central nervous system (CNS) tumors are the most common solid tumor in children, with the majority being glial in origin. These tumors are classified by the World Health Organization (WHO) as either being low grade (WHO grade 1 and 2) or high grade (WHO grade 3 and 4). Our knowledge of the molecular landscape of pediatric brain tumors has advanced over the last decade, which has led to newer categorizations along with an expansion of therapeutic targets and options. In this review, we will give an overview of common CNS tumors seen in children along with a focus on treatment options and future considerations. |
| first_indexed | 2024-03-11T01:14:44Z |
| format | Article |
| id | doaj.art-8953e2dc87ac4ae59492ab4409220fad |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-11T01:14:44Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-8953e2dc87ac4ae59492ab4409220fad2023-11-18T18:35:25ZengMDPI AGBrain Sciences2076-34252023-07-01137110610.3390/brainsci13071106Pediatric Central Nervous System Tumor Overview and Emerging Treatment ConsiderationsSudarshawn Damodharan0Diane Puccetti1Department of Pediatrics, Division of Pediatric Hematology, Oncology and Bone Marrow Transplant, University of Wisconsin School of Medicine & Public Health, Madison, WI 53792, USADepartment of Pediatrics, Division of Pediatric Hematology, Oncology and Bone Marrow Transplant, University of Wisconsin School of Medicine & Public Health, Madison, WI 53792, USAPediatric central nervous system (CNS) tumors are the most common solid tumor in children, with the majority being glial in origin. These tumors are classified by the World Health Organization (WHO) as either being low grade (WHO grade 1 and 2) or high grade (WHO grade 3 and 4). Our knowledge of the molecular landscape of pediatric brain tumors has advanced over the last decade, which has led to newer categorizations along with an expansion of therapeutic targets and options. In this review, we will give an overview of common CNS tumors seen in children along with a focus on treatment options and future considerations.https://www.mdpi.com/2076-3425/13/7/1106pediatricsCNStumorstreatmentmolecular |
| spellingShingle | Sudarshawn Damodharan Diane Puccetti Pediatric Central Nervous System Tumor Overview and Emerging Treatment Considerations Brain Sciences pediatrics CNS tumors treatment molecular |
| title | Pediatric Central Nervous System Tumor Overview and Emerging Treatment Considerations |
| title_full | Pediatric Central Nervous System Tumor Overview and Emerging Treatment Considerations |
| title_fullStr | Pediatric Central Nervous System Tumor Overview and Emerging Treatment Considerations |
| title_full_unstemmed | Pediatric Central Nervous System Tumor Overview and Emerging Treatment Considerations |
| title_short | Pediatric Central Nervous System Tumor Overview and Emerging Treatment Considerations |
| title_sort | pediatric central nervous system tumor overview and emerging treatment considerations |
| topic | pediatrics CNS tumors treatment molecular |
| url | https://www.mdpi.com/2076-3425/13/7/1106 |
| work_keys_str_mv | AT sudarshawndamodharan pediatriccentralnervoussystemtumoroverviewandemergingtreatmentconsiderations AT dianepuccetti pediatriccentralnervoussystemtumoroverviewandemergingtreatmentconsiderations |