Synthesis and antioxidant activity of novel 8-formyl-4-substitued coumarins

4-Methyl-8-formyl- and 4-phenyl-8-formyl coumarins have been synthesized by Pechmann reaction using oxalic acid catalyst for the first time. 4-Propyl-7-hydroxy-, and 4-methyl-7-methoxy coumarins have also been accomplished by this catalyst for the first time. They have been characterizated by IR, 1H...

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Main Authors: H. Ç. Onar, B. A.Vardar
Format: Article
Language:English
Published: Chemical Society of Ethiopia 2018-04-01
Series:Bulletin of the Chemical Society of Ethiopia
Subjects:
Online Access:https://www.ajol.info/index.php/bcse/article/view/169545
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author H. Ç. Onar
B. A.Vardar
author_facet H. Ç. Onar
B. A.Vardar
author_sort H. Ç. Onar
collection DOAJ
description 4-Methyl-8-formyl- and 4-phenyl-8-formyl coumarins have been synthesized by Pechmann reaction using oxalic acid catalyst for the first time. 4-Propyl-7-hydroxy-, and 4-methyl-7-methoxy coumarins have also been accomplished by this catalyst for the first time. They have been characterizated by IR, 1H-NMR, 13C-NMR, mass and elemental analysis. Furthermore, the obtained coumarins were compared according to antioxidant activity by DPPH method.
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spelling doaj.art-89551b886b4a45dc9cf6b317135159e42022-12-21T22:51:12ZengChemical Society of EthiopiaBulletin of the Chemical Society of Ethiopia1011-39241726-801X2018-04-01321175178https://dx.doi.org/10.4314/bcse.v32i1.17Synthesis and antioxidant activity of novel 8-formyl-4-substitued coumarinsH. Ç. OnarB. A.Vardar4-Methyl-8-formyl- and 4-phenyl-8-formyl coumarins have been synthesized by Pechmann reaction using oxalic acid catalyst for the first time. 4-Propyl-7-hydroxy-, and 4-methyl-7-methoxy coumarins have also been accomplished by this catalyst for the first time. They have been characterizated by IR, 1H-NMR, 13C-NMR, mass and elemental analysis. Furthermore, the obtained coumarins were compared according to antioxidant activity by DPPH method.https://www.ajol.info/index.php/bcse/article/view/169545CoumarinAntioxidant activityDPPH method
spellingShingle H. Ç. Onar
B. A.Vardar
Synthesis and antioxidant activity of novel 8-formyl-4-substitued coumarins
Bulletin of the Chemical Society of Ethiopia
Coumarin
Antioxidant activity
DPPH method
title Synthesis and antioxidant activity of novel 8-formyl-4-substitued coumarins
title_full Synthesis and antioxidant activity of novel 8-formyl-4-substitued coumarins
title_fullStr Synthesis and antioxidant activity of novel 8-formyl-4-substitued coumarins
title_full_unstemmed Synthesis and antioxidant activity of novel 8-formyl-4-substitued coumarins
title_short Synthesis and antioxidant activity of novel 8-formyl-4-substitued coumarins
title_sort synthesis and antioxidant activity of novel 8 formyl 4 substitued coumarins
topic Coumarin
Antioxidant activity
DPPH method
url https://www.ajol.info/index.php/bcse/article/view/169545
work_keys_str_mv AT hconar synthesisandantioxidantactivityofnovel8formyl4substituedcoumarins
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