Blocking Thrombin Significantly Ameliorates Experimental Autoimmune Neuritis

Blocking Thrombin Significantly Ameliorates Experimental Autoimmune Neuritis

Thrombin and its protease-activated receptor 1 (PAR1) are potentially important in peripheral nerve inflammatory diseases. We studied the role of thrombin and PAR1 in rat experimental autoimmune neuritis (EAN), a model of the human Guillain-Barré syndrome (GBS). EAN was induced by bovine peripheral...

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Bibliographic Details
Main Authors:	Efrat Shavit-Stein, Ramona Aronovich, Constantin Sylantiev, Orna Gera, Shany G. Gofrit, Joab Chapman, Amir Dori
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-01-01
Series:	Frontiers in Neurology
Subjects:	thrombin experimental autoimmune neuritis node of Ranvier PAR1 Guillain-Barré syndrome
Online Access:	https://www.frontiersin.org/article/10.3389/fneur.2018.01139/full

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