Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first One‐Centre experience with TDM
Abstract The aim of this article is to demonstrate extreme interindividual variability of piperacilin/tazobactam (PIP/TAZO) pharmacokinetics in critically ill morbidly obese patients and to emphasize the need for the practice of routine PIP/TAZO plasma concentrations measurement in order to ensure o...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-03-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.7032 |
| _version_ | 1827976461211926528 |
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| author | M. Mieresova K. Balazova J. Kubele D. Cerny M. Halacova |
| author_facet | M. Mieresova K. Balazova J. Kubele D. Cerny M. Halacova |
| author_sort | M. Mieresova |
| collection | DOAJ |
| description | Abstract The aim of this article is to demonstrate extreme interindividual variability of piperacilin/tazobactam (PIP/TAZO) pharmacokinetics in critically ill morbidly obese patients and to emphasize the need for the practice of routine PIP/TAZO plasma concentrations measurement in order to ensure optimal efficacy and safety of antibiotic therapy. |
| first_indexed | 2024-04-09T20:35:49Z |
| format | Article |
| id | doaj.art-895e9ea7aa6d4f1abcd12a404ab73904 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-04-09T20:35:49Z |
| publishDate | 2023-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-895e9ea7aa6d4f1abcd12a404ab739042023-03-30T10:21:24ZengWileyClinical Case Reports2050-09042023-03-01113n/an/a10.1002/ccr3.7032Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first One‐Centre experience with TDMM. Mieresova0K. Balazova1J. Kubele2D. Cerny3M. Halacova4Department of Clinical Pharmacy Na Homolce Hospital Prague Czech RepublicDepartment of Clinical Pharmacy Na Homolce Hospital Prague Czech RepublicDepartment of Clinical Microbiology and Antibiotic Surveillance Na Homolce Hospital Prague Czech RepublicDepartment of Clinical Pharmacy Na Homolce Hospital Prague Czech RepublicDepartment of Clinical Pharmacy Na Homolce Hospital Prague Czech RepublicAbstract The aim of this article is to demonstrate extreme interindividual variability of piperacilin/tazobactam (PIP/TAZO) pharmacokinetics in critically ill morbidly obese patients and to emphasize the need for the practice of routine PIP/TAZO plasma concentrations measurement in order to ensure optimal efficacy and safety of antibiotic therapy.https://doi.org/10.1002/ccr3.7032critical illnessmorbid obesitypiperacillin/tazobactam (PIP/TAZO)therapeutic drug monitoring (TDM) |
| spellingShingle | M. Mieresova K. Balazova J. Kubele D. Cerny M. Halacova Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first One‐Centre experience with TDM Clinical Case Reports critical illness morbid obesity piperacillin/tazobactam (PIP/TAZO) therapeutic drug monitoring (TDM) |
| title | Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first One‐Centre experience with TDM |
| title_full | Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first One‐Centre experience with TDM |
| title_fullStr | Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first One‐Centre experience with TDM |
| title_full_unstemmed | Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first One‐Centre experience with TDM |
| title_short | Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first One‐Centre experience with TDM |
| title_sort | piperacillin tazobactam in critically ill morbidly obese patients a case series the first one centre experience with tdm |
| topic | critical illness morbid obesity piperacillin/tazobactam (PIP/TAZO) therapeutic drug monitoring (TDM) |
| url | https://doi.org/10.1002/ccr3.7032 |
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