Comparison of the Single Cell Immune Landscape between Subjects with High <i>Mycobacterium tuberculosis</i> Bacillary Loads during Active Pulmonary Tuberculosis and Household Members with Latent Tuberculosis Infection

Comparison of the Single Cell Immune Landscape between Subjects with High <i>Mycobacterium tuberculosis</i> Bacillary Loads during Active Pulmonary Tuberculosis and Household Members with Latent Tuberculosis Infection

It is unclear how the immune system controls the transition from latent tuberculosis (TB) infection (LTBI) to active pulmonary infection (PTB). Here, we applied mass spectrometry cytometry time-of-flight (CyTOF) analysis of peripheral blood mononuclear cells to compare the immunological landscapes i...

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Bibliographic Details
Main Authors: Supitcha Kamolratanakul, Wassawon Ariyanon, Kanyarat Udompornpitak, Thansita Bhunyakarnjanarat, Asada Leelahavanichkul, Jittima Dhitavat, Polrat Wilairatana, Wiwat Chancharoenthana
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cells
Subjects:
CyTOF
latent tuberculosis
pulmonary
responder
tuberculosis
Online Access:https://www.mdpi.com/2073-4409/13/4/362

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