Potent human neutralizing antibodies against Nipah virus derived from two ancestral antibody heavy chains

Potent human neutralizing antibodies against Nipah virus derived from two ancestral antibody heavy chains

Abstract Nipah virus (NiV) is a World Health Organization priority pathogen and there are currently no approved drugs for clinical immunotherapy. Through the use of a naïve human phage-displayed Fab library, two neutralizing antibodies (NiV41 and NiV42) targeting the NiV receptor binding protein (RB...

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Bibliographic Details
Main Authors:	Li Chen, Mengmeng Sun, Huajun Zhang, Xinghai Zhang, Yanfeng Yao, Ming Li, Kangyin Li, Pengfei Fan, Haiwei Zhang, Ye Qin, Zhe Zhang, Entao Li, Zhen Chen, Wuxiang Guan, Shanshan Li, Changming Yu, Kaiming Zhang, Rui Gong, Sandra Chiu
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-04-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-024-47213-8

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