Total skin electron beam therapy (TSEBT) in management of mycosis fungoides: a case series

In Aga Khan University, a retrospective review was conducted from January 2013-December 2020 for patients who received Total Skin Electron Beam Therapy (TSEBT) for the management of Mycosis Fungoides (MF). The clinical response rate and disease-free interval (DFI) was evaluated for three patients....

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Main Authors: Sehrish Abrar, Bilal Mazhar Qureshi, Asim Hafiz, Nasir Ali, Agha Mohammad Hammad Khan, Ahmed Nadeem Abbasi
Format: Article
Language:English
Published: Pakistan Medical Association 2022-02-01
Series:Journal of the Pakistan Medical Association
Online Access:https://www.ojs.jpma.org.pk/index.php/public_html/article/view/3784
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author Sehrish Abrar
Bilal Mazhar Qureshi
Asim Hafiz
Nasir Ali
Agha Mohammad Hammad Khan
Ahmed Nadeem Abbasi
author_facet Sehrish Abrar
Bilal Mazhar Qureshi
Asim Hafiz
Nasir Ali
Agha Mohammad Hammad Khan
Ahmed Nadeem Abbasi
author_sort Sehrish Abrar
collection DOAJ
description In Aga Khan University, a retrospective review was conducted from January 2013-December 2020 for patients who received Total Skin Electron Beam Therapy (TSEBT) for the management of Mycosis Fungoides (MF). The clinical response rate and disease-free interval (DFI) was evaluated for three patients. All of the patients received a 3600 cGy dose of radiation. Clinical complete remission (cCR) was observed in two out of three patients, while one patient showed clinical partial response. Following the cCR to TSEBT, the DFI of the first patient with stage 1B lasted 30 months, while the second patient with stage IIB remained disease free for five months. TSEBT is an effective treatment for MF disease. It can thus be expected that patients with limited disease in the early stage can acquire a cCR with a longer DFI. ---Continue
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spelling doaj.art-8962e30e5def438d8fa1a71fa13966c02023-05-25T04:22:50ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822022-02-0172610.47391/JPMA.3784Total skin electron beam therapy (TSEBT) in management of mycosis fungoides: a case seriesSehrish Abrar0Bilal Mazhar Qureshi1Asim Hafiz2Nasir Ali3Agha Mohammad Hammad Khan4Ahmed Nadeem Abbasi5Department of Oncology, Aga Khan University Hospital, Karachi, PakistanDepartment of Oncology, Aga Khan University Hospital, Karachi, PakistanDepartment of Oncology, Aga Khan University Hospital, Karachi, PakistanDepartment of Oncology, Aga Khan University Hospital, Karachi, PakistanDepartment of Oncology, Aga Khan University Hospital, Karachi, PakistanDepartment of Oncology, Aga Khan University Hospital, Karachi, Pakistan In Aga Khan University, a retrospective review was conducted from January 2013-December 2020 for patients who received Total Skin Electron Beam Therapy (TSEBT) for the management of Mycosis Fungoides (MF). The clinical response rate and disease-free interval (DFI) was evaluated for three patients. All of the patients received a 3600 cGy dose of radiation. Clinical complete remission (cCR) was observed in two out of three patients, while one patient showed clinical partial response. Following the cCR to TSEBT, the DFI of the first patient with stage 1B lasted 30 months, while the second patient with stage IIB remained disease free for five months. TSEBT is an effective treatment for MF disease. It can thus be expected that patients with limited disease in the early stage can acquire a cCR with a longer DFI. ---Continue https://www.ojs.jpma.org.pk/index.php/public_html/article/view/3784
spellingShingle Sehrish Abrar
Bilal Mazhar Qureshi
Asim Hafiz
Nasir Ali
Agha Mohammad Hammad Khan
Ahmed Nadeem Abbasi
Total skin electron beam therapy (TSEBT) in management of mycosis fungoides: a case series
Journal of the Pakistan Medical Association
title Total skin electron beam therapy (TSEBT) in management of mycosis fungoides: a case series
title_full Total skin electron beam therapy (TSEBT) in management of mycosis fungoides: a case series
title_fullStr Total skin electron beam therapy (TSEBT) in management of mycosis fungoides: a case series
title_full_unstemmed Total skin electron beam therapy (TSEBT) in management of mycosis fungoides: a case series
title_short Total skin electron beam therapy (TSEBT) in management of mycosis fungoides: a case series
title_sort total skin electron beam therapy tsebt in management of mycosis fungoides a case series
url https://www.ojs.jpma.org.pk/index.php/public_html/article/view/3784
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