Catalysts for Change: The Role of Nonprofits in Solving Single Ventricle Heart Disease
Single ventricle (SV) heart disease comprises a spectrum of complex congenital heart defects (CHDs), including hypoplastic left heart syndrome (HLHS), one of the most common causes of death amongst infants with CHD. Despite its incompletely defined etiology and a dearth of curative solutions, SV is...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Journal of Cardiovascular Development and Disease |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2308-3425/9/7/220 |
| _version_ | 1827596971252121600 |
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| author | Kaitlin A. Davis Diane M. Pickles Kirstie E. Keller |
| author_facet | Kaitlin A. Davis Diane M. Pickles Kirstie E. Keller |
| author_sort | Kaitlin A. Davis |
| collection | DOAJ |
| description | Single ventricle (SV) heart disease comprises a spectrum of complex congenital heart defects (CHDs), including hypoplastic left heart syndrome (HLHS), one of the most common causes of death amongst infants with CHD. Despite its incompletely defined etiology and a dearth of curative solutions, SV is a solvable problem that can be addressed by unifying a nascent field that is ripe for investment, in part due to its high economic impact and growth potential. Here, we explore the landscape of SV and identify areas of opportunity that will yield an outsized impact through strategic investment that focuses on synchronization across disciplines, community involvement, and infrastructure development, and argue that nonprofits are the appropriate catalyst to spark transformative innovation and impact in the form of functional cures. |
| first_indexed | 2024-03-09T03:20:27Z |
| format | Article |
| id | doaj.art-8963d3ca667e4bd0a071132fdae41425 |
| institution | Directory Open Access Journal |
| issn | 2308-3425 |
| language | English |
| last_indexed | 2024-03-09T03:20:27Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Cardiovascular Development and Disease |
| spelling | doaj.art-8963d3ca667e4bd0a071132fdae414252023-12-03T15:12:11ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252022-07-019722010.3390/jcdd9070220Catalysts for Change: The Role of Nonprofits in Solving Single Ventricle Heart DiseaseKaitlin A. Davis0Diane M. Pickles1Kirstie E. Keller2Additional Ventures, Palo Alto, CA 94301, USAAdditional Ventures, Palo Alto, CA 94301, USAAdditional Ventures, Palo Alto, CA 94301, USASingle ventricle (SV) heart disease comprises a spectrum of complex congenital heart defects (CHDs), including hypoplastic left heart syndrome (HLHS), one of the most common causes of death amongst infants with CHD. Despite its incompletely defined etiology and a dearth of curative solutions, SV is a solvable problem that can be addressed by unifying a nascent field that is ripe for investment, in part due to its high economic impact and growth potential. Here, we explore the landscape of SV and identify areas of opportunity that will yield an outsized impact through strategic investment that focuses on synchronization across disciplines, community involvement, and infrastructure development, and argue that nonprofits are the appropriate catalyst to spark transformative innovation and impact in the form of functional cures.https://www.mdpi.com/2308-3425/9/7/220single ventriclecongenital heart diseasefunding strategiesnonprofitphilanthropy |
| spellingShingle | Kaitlin A. Davis Diane M. Pickles Kirstie E. Keller Catalysts for Change: The Role of Nonprofits in Solving Single Ventricle Heart Disease Journal of Cardiovascular Development and Disease single ventricle congenital heart disease funding strategies nonprofit philanthropy |
| title | Catalysts for Change: The Role of Nonprofits in Solving Single Ventricle Heart Disease |
| title_full | Catalysts for Change: The Role of Nonprofits in Solving Single Ventricle Heart Disease |
| title_fullStr | Catalysts for Change: The Role of Nonprofits in Solving Single Ventricle Heart Disease |
| title_full_unstemmed | Catalysts for Change: The Role of Nonprofits in Solving Single Ventricle Heart Disease |
| title_short | Catalysts for Change: The Role of Nonprofits in Solving Single Ventricle Heart Disease |
| title_sort | catalysts for change the role of nonprofits in solving single ventricle heart disease |
| topic | single ventricle congenital heart disease funding strategies nonprofit philanthropy |
| url | https://www.mdpi.com/2308-3425/9/7/220 |
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