Subcutaneous ω-Conotoxins Alleviate Mechanical Pain in Rodent Models of Acute Peripheral Neuropathy

Subcutaneous ω-Conotoxins Alleviate Mechanical Pain in Rodent Models of Acute Peripheral Neuropathy

The peripheral effects of ω-conotoxins, selective blockers of N-type voltage-gated calcium channels (Ca<sub>V</sub>2.2), have not been characterised across different clinically relevant pain models. This study examines the effects of locally administered ω-conotoxin MVIIA, GVIA, and CVIF...

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Bibliographic Details
Main Authors: Md. Mahadhi Hasan, Hana Starobova, Alexander Mueller, Irina Vetter, Richard J. Lewis
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Marine Drugs
Subjects:
ω-conotoxins
chemotherapy-induced peripheral neuropathy
postsurgical pain
intraplantar administration
Online Access:https://www.mdpi.com/1660-3397/19/2/106

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