CARDIAC MAGNETIC RESONANCE IMAGING IN DIFFERENTIAL DIAGNOSTICS OF ACUTE CORONARY SYNDROME IN PATIENTS WITH NON-OBSTRUCTION CORONARY ATHEROSCLEROSIS
Aim. To investigate on the nosological structure of acute coronary syndrome (ACS) in patients with non-obstruction coronary atherosclerosis (NOCA) before and after magnetic resonance imaging (MRI) of the heart.Material and methods. A non-randomized, open, controlled study (NCT02655718). The patients...
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«FIRMA «SILICEA» LLC
2017-12-01
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author | V. V. Ryabov S. B. Gomboeva Т. A. Shelkovnikova A. Е. Baev М. S. Rebenkova Yu. V. Rogovskaya V. Yu. Usov |
author_facet | V. V. Ryabov S. B. Gomboeva Т. A. Shelkovnikova A. Е. Baev М. S. Rebenkova Yu. V. Rogovskaya V. Yu. Usov |
author_sort | V. V. Ryabov |
collection | DOAJ |
description | Aim. To investigate on the nosological structure of acute coronary syndrome (ACS) in patients with non-obstruction coronary atherosclerosis (NOCA) before and after magnetic resonance imaging (MRI) of the heart.Material and methods. A non-randomized, open, controlled study (NCT02655718). The patients included, with ACS, older than 18 y.o., with NOCA (intact coronary arteries or stenosis ≤50%) confirmed by invasive coronary arteriography (ICAG). Patients with previous revascularization were not included.Results. In the year 2016, to emergency cardiology department (ECD) 913 ACS patients admitted. In 44 (4,8%) the NOCA was found. Mean age 54±10,4 y.o., males 68%, and the groups with ACS with ST elevation (STEACS) and none (NSTEANS) were comparable by clinical and anamnestic parameters. Intact coronary arteries were visualized in 16 (53%), non-significant coronary atherosclerosis was diagnosed in 14 (32%), slower coronary flow — 22 (73%). By MRI with contrast, performed in 11±8 days (2-43 days) from ACS beginning, myocardial oedema was found in 18 (41%), hyperemia in 13 (30%) and fibrosis in 40 (91%); there were no changes in 1 patient.Nosological structure of ACS in NOCA after MRI has been represented: by acute myocardial infarction (MI) in 24 (55%) cases, unstable angina (UA) — in 6 (14%), pseudocoronary myocarditis in 10 (23%), acute aorta dissection in 1 (2%), posttraumatic atherosclerosis in 1 (2%), congenital valve defect in 1 (2%), manifested Wolf-Parkinson-White (WPW) — in 1 (2%). In-hospital mortality was 2%. In comparison of ACS before and post MRI there was significant increase number of patients with myocarditis, by 20%.Conclusion. The prevalence of ACS in NOCA is 4,8%, that is comparable to literature data. Patients with ACS and NOCA are heterogenic group with MI, UA, myocarditis, acute aorta dissection, posttraumatic atherosclerosis, congenital defects, WPW syndrome. In-hospital mortality was 2%. Comparing the structure of the diagnoses before and after MRI, there was significant increase of myocarditis patients number. A high accuracy of MRI was found for differential diagnostics of ACS in NOCA, which was 78%. |
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spelling | doaj.art-8968c3ef965f4af5a90fe9efc8f65b262023-03-29T21:23:29Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202017-12-01012475410.15829/1560-4071-2017-12-47-542165CARDIAC MAGNETIC RESONANCE IMAGING IN DIFFERENTIAL DIAGNOSTICS OF ACUTE CORONARY SYNDROME IN PATIENTS WITH NON-OBSTRUCTION CORONARY ATHEROSCLEROSISV. V. Ryabov0S. B. Gomboeva1Т. A. Shelkovnikova2A. Е. Baev3М. S. Rebenkova4Yu. V. Rogovskaya5V. Yu. Usov6Cardiology Research Institute, Tomsk National Research Medical Centre of RAS; National Research Tomsk State University; Siberian State Medical University (SSMU)Cardiology Research Institute, Tomsk National Research Medical Centre of RAS; National Research Tomsk State UniversityCardiology Research Institute, Tomsk National Research Medical Centre of RASCardiology Research Institute, Tomsk National Research Medical Centre of RASCardiology Research Institute, Tomsk National Research Medical Centre of RAS; National Research Tomsk State UniversityCardiology Research Institute, Tomsk National Research Medical Centre of RAS; National Research Tomsk State UniversityCardiology Research Institute, Tomsk National Research Medical Centre of RASAim. To investigate on the nosological structure of acute coronary syndrome (ACS) in patients with non-obstruction coronary atherosclerosis (NOCA) before and after magnetic resonance imaging (MRI) of the heart.Material and methods. A non-randomized, open, controlled study (NCT02655718). The patients included, with ACS, older than 18 y.o., with NOCA (intact coronary arteries or stenosis ≤50%) confirmed by invasive coronary arteriography (ICAG). Patients with previous revascularization were not included.Results. In the year 2016, to emergency cardiology department (ECD) 913 ACS patients admitted. In 44 (4,8%) the NOCA was found. Mean age 54±10,4 y.o., males 68%, and the groups with ACS with ST elevation (STEACS) and none (NSTEANS) were comparable by clinical and anamnestic parameters. Intact coronary arteries were visualized in 16 (53%), non-significant coronary atherosclerosis was diagnosed in 14 (32%), slower coronary flow — 22 (73%). By MRI with contrast, performed in 11±8 days (2-43 days) from ACS beginning, myocardial oedema was found in 18 (41%), hyperemia in 13 (30%) and fibrosis in 40 (91%); there were no changes in 1 patient.Nosological structure of ACS in NOCA after MRI has been represented: by acute myocardial infarction (MI) in 24 (55%) cases, unstable angina (UA) — in 6 (14%), pseudocoronary myocarditis in 10 (23%), acute aorta dissection in 1 (2%), posttraumatic atherosclerosis in 1 (2%), congenital valve defect in 1 (2%), manifested Wolf-Parkinson-White (WPW) — in 1 (2%). In-hospital mortality was 2%. In comparison of ACS before and post MRI there was significant increase number of patients with myocarditis, by 20%.Conclusion. The prevalence of ACS in NOCA is 4,8%, that is comparable to literature data. Patients with ACS and NOCA are heterogenic group with MI, UA, myocarditis, acute aorta dissection, posttraumatic atherosclerosis, congenital defects, WPW syndrome. In-hospital mortality was 2%. Comparing the structure of the diagnoses before and after MRI, there was significant increase of myocarditis patients number. A high accuracy of MRI was found for differential diagnostics of ACS in NOCA, which was 78%.https://russjcardiol.elpub.ru/jour/article/view/1557acute coronary syndromenon-obstructive coronary atherosclerosismagnetic resonance tomographymyocardial infarctionmyocarditis |
spellingShingle | V. V. Ryabov S. B. Gomboeva Т. A. Shelkovnikova A. Е. Baev М. S. Rebenkova Yu. V. Rogovskaya V. Yu. Usov CARDIAC MAGNETIC RESONANCE IMAGING IN DIFFERENTIAL DIAGNOSTICS OF ACUTE CORONARY SYNDROME IN PATIENTS WITH NON-OBSTRUCTION CORONARY ATHEROSCLEROSIS Российский кардиологический журнал acute coronary syndrome non-obstructive coronary atherosclerosis magnetic resonance tomography myocardial infarction myocarditis |
title | CARDIAC MAGNETIC RESONANCE IMAGING IN DIFFERENTIAL DIAGNOSTICS OF ACUTE CORONARY SYNDROME IN PATIENTS WITH NON-OBSTRUCTION CORONARY ATHEROSCLEROSIS |
title_full | CARDIAC MAGNETIC RESONANCE IMAGING IN DIFFERENTIAL DIAGNOSTICS OF ACUTE CORONARY SYNDROME IN PATIENTS WITH NON-OBSTRUCTION CORONARY ATHEROSCLEROSIS |
title_fullStr | CARDIAC MAGNETIC RESONANCE IMAGING IN DIFFERENTIAL DIAGNOSTICS OF ACUTE CORONARY SYNDROME IN PATIENTS WITH NON-OBSTRUCTION CORONARY ATHEROSCLEROSIS |
title_full_unstemmed | CARDIAC MAGNETIC RESONANCE IMAGING IN DIFFERENTIAL DIAGNOSTICS OF ACUTE CORONARY SYNDROME IN PATIENTS WITH NON-OBSTRUCTION CORONARY ATHEROSCLEROSIS |
title_short | CARDIAC MAGNETIC RESONANCE IMAGING IN DIFFERENTIAL DIAGNOSTICS OF ACUTE CORONARY SYNDROME IN PATIENTS WITH NON-OBSTRUCTION CORONARY ATHEROSCLEROSIS |
title_sort | cardiac magnetic resonance imaging in differential diagnostics of acute coronary syndrome in patients with non obstruction coronary atherosclerosis |
topic | acute coronary syndrome non-obstructive coronary atherosclerosis magnetic resonance tomography myocardial infarction myocarditis |
url | https://russjcardiol.elpub.ru/jour/article/view/1557 |
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