Critical Molecular and Cellular Contributors to Tau Pathology

Critical Molecular and Cellular Contributors to Tau Pathology

Tauopathies represent a group of neurodegenerative diseases including Alzheimer’s disease (AD) that are characterized by the deposition of filamentous tau aggregates in the brain. The pathogenesis of tauopathies starts from the formation of toxic ‘tau seeds’ from hyperphosphorylated tau monomers. Th...

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Bibliographic Details
Main Authors: Liqing Song, Evan A. Wells, Anne Skaja Robinson
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Biomedicines
Subjects:
tauopathies
Alzheimer’s disease
prion-like propagation
tau self-aggregation
endocytosis
neuron-glial communication
Online Access:https://www.mdpi.com/2227-9059/9/2/190

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