Decision Tool for Herpes B Virus Antiviral Prophylaxis after Macaque-Related Injuries in Research Laboratory Workers
Macaque-related injuries among primate workers can lead to a potentially fatal B virus encephalomyelitis. We describe a decision tool for evaluating the need for antiviral postexposure prophylaxis and provide a retrospective review of the injuries assessed in our center after its implementation in 2...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Centers for Disease Control and Prevention
2019-09-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/25/9/19-0045_article |
| _version_ | 1818483141733515264 |
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| author | Sapha Barkati Hashim Ba Taher Elizabeth Beauchamp Cédric P. Yansouni Brian J. Ward Michael D. Libman |
| author_facet | Sapha Barkati Hashim Ba Taher Elizabeth Beauchamp Cédric P. Yansouni Brian J. Ward Michael D. Libman |
| author_sort | Sapha Barkati |
| collection | DOAJ |
| description | Macaque-related injuries among primate workers can lead to a potentially fatal B virus encephalomyelitis. We describe a decision tool for evaluating the need for antiviral postexposure prophylaxis and provide a retrospective review of the injuries assessed in our center after its implementation in 2010. Among the injuries studied (n = 251), 40.6% were categorized as high-risk (prophylaxis recommended), 44.2% moderate-risk (consider prophylaxis), and 15.1% low-risk (prophylaxis not recommended). Ten percent of low-risk and 98% of high-risk injuries received prophylaxis (p<0.001). Compared with using universal postexposure prophylaxis, using a decision tool can lead to a standardization of practice and a reduction in prescriptions for antiviral medication. |
| first_indexed | 2024-12-10T11:56:25Z |
| format | Article |
| id | doaj.art-896b0230edec4da1ba1298a9f976f0b6 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-10T11:56:25Z |
| publishDate | 2019-09-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-896b0230edec4da1ba1298a9f976f0b62022-12-22T01:49:45ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592019-09-012591610.3201/eid2509.190045Decision Tool for Herpes B Virus Antiviral Prophylaxis after Macaque-Related Injuries in Research Laboratory WorkersSapha BarkatiHashim Ba TaherElizabeth BeauchampCédric P. YansouniBrian J. WardMichael D. LibmanMacaque-related injuries among primate workers can lead to a potentially fatal B virus encephalomyelitis. We describe a decision tool for evaluating the need for antiviral postexposure prophylaxis and provide a retrospective review of the injuries assessed in our center after its implementation in 2010. Among the injuries studied (n = 251), 40.6% were categorized as high-risk (prophylaxis recommended), 44.2% moderate-risk (consider prophylaxis), and 15.1% low-risk (prophylaxis not recommended). Ten percent of low-risk and 98% of high-risk injuries received prophylaxis (p<0.001). Compared with using universal postexposure prophylaxis, using a decision tool can lead to a standardization of practice and a reduction in prescriptions for antiviral medication.https://wwwnc.cdc.gov/eid/article/25/9/19-0045_articleherpes B virus infectionB virusmonkey B virusmacacine alphaherpesvirus 1macaqueantiviral agents |
| spellingShingle | Sapha Barkati Hashim Ba Taher Elizabeth Beauchamp Cédric P. Yansouni Brian J. Ward Michael D. Libman Decision Tool for Herpes B Virus Antiviral Prophylaxis after Macaque-Related Injuries in Research Laboratory Workers Emerging Infectious Diseases herpes B virus infection B virus monkey B virus macacine alphaherpesvirus 1 macaque antiviral agents |
| title | Decision Tool for Herpes B Virus Antiviral Prophylaxis after Macaque-Related Injuries in Research Laboratory Workers |
| title_full | Decision Tool for Herpes B Virus Antiviral Prophylaxis after Macaque-Related Injuries in Research Laboratory Workers |
| title_fullStr | Decision Tool for Herpes B Virus Antiviral Prophylaxis after Macaque-Related Injuries in Research Laboratory Workers |
| title_full_unstemmed | Decision Tool for Herpes B Virus Antiviral Prophylaxis after Macaque-Related Injuries in Research Laboratory Workers |
| title_short | Decision Tool for Herpes B Virus Antiviral Prophylaxis after Macaque-Related Injuries in Research Laboratory Workers |
| title_sort | decision tool for herpes b virus antiviral prophylaxis after macaque related injuries in research laboratory workers |
| topic | herpes B virus infection B virus monkey B virus macacine alphaherpesvirus 1 macaque antiviral agents |
| url | https://wwwnc.cdc.gov/eid/article/25/9/19-0045_article |
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