Maternal pravastatin prevents altered fetal brain development in a preeclamptic CD-1 mouse model.

Maternal pravastatin prevents altered fetal brain development in a preeclamptic CD-1 mouse model.

Using an animal model, we have previously shown that preeclampsia results in long-term adverse neuromotor outcomes in the offspring, and this phenotype was prevented by antenatal treatment with pravastatin. This study aims to localize the altered neuromotor programming in this animal model and to ev...

Full description

Bibliographic Details
Main Authors: Alissa R Carver, Maria Andrikopoulou, Jun Lei, Esther Tamayo, Phyllis Gamble, Zhipeng Hou, Jiangyang Zhang, Susumu Mori, George R Saade, Maged M Costantine, Irina Burd
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4071009?pdf=render

Similar Items

Similar Items