Emerging microfluidics for the modeling and treatment of arthritis

Microfluidic is a technology that allows the precise control of fluid in a micro-channel. With its advantages of high throughput and low cost, microfluidic technology has achieved good performance in various fields in recent years. Arthritis is a general term for a variety of joint diseases, which c...

Full description

Bibliographic Details
Main Authors: Nengjie Yang, Chi Sun, Chen Dong, Yuting Huang, Yujuan Zhu, Zhifeng Gu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-06-01
Series:Engineered Regeneration
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666138124000124
_version_ 1797268984621432832
author Nengjie Yang
Chi Sun
Chen Dong
Yuting Huang
Yujuan Zhu
Zhifeng Gu
author_facet Nengjie Yang
Chi Sun
Chen Dong
Yuting Huang
Yujuan Zhu
Zhifeng Gu
author_sort Nengjie Yang
collection DOAJ
description Microfluidic is a technology that allows the precise control of fluid in a micro-channel. With its advantages of high throughput and low cost, microfluidic technology has achieved good performance in various fields in recent years. Arthritis is a general term for a variety of joint diseases, which can be clinically manifested as joint pain and swelling, seriously affecting people's physical and mental health. At present, the causes of arthritis disease are still unknown, and existing disease models and treatment methods are still limited, so more treatments need to be developed. Microfluidic organ chip is a cutting-edge technology to build a bionic human organ model, which can reflect the structure and function characteristics of human organs by simulating the physiological environment of tissues and cells in vitro. This paper reviews the application of microfluidic technology in the modeling and treatment of arthritis, hoping to open up a new vision for the study of arthritis.
first_indexed 2024-04-25T01:41:10Z
format Article
id doaj.art-89780776ec804d339d5610a924ce7b65
institution Directory Open Access Journal
issn 2666-1381
language English
last_indexed 2024-04-25T01:41:10Z
publishDate 2024-06-01
publisher KeAi Communications Co., Ltd.
record_format Article
series Engineered Regeneration
spelling doaj.art-89780776ec804d339d5610a924ce7b652024-03-08T05:19:32ZengKeAi Communications Co., Ltd.Engineered Regeneration2666-13812024-06-0152153169Emerging microfluidics for the modeling and treatment of arthritisNengjie Yang0Chi Sun1Chen Dong2Yuting Huang3Yujuan Zhu4Zhifeng Gu5Department of Rheumatology, Research Center of Immunology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, ChinaDepartment of Geriatrics, Affiliated Hospital of Nantong University, Nantong University, Nantong 226001, ChinaDepartment of Rheumatology, Research Center of Immunology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, ChinaDepartment of Dermatology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, ChinaResearch Center of Clinical Medicine, Research Center of Immunology, Affiliated Hospital of Nantong University, Nantong 226001, China; Corresponding authors.Department of Rheumatology, Research Center of Immunology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China; Corresponding authors.Microfluidic is a technology that allows the precise control of fluid in a micro-channel. With its advantages of high throughput and low cost, microfluidic technology has achieved good performance in various fields in recent years. Arthritis is a general term for a variety of joint diseases, which can be clinically manifested as joint pain and swelling, seriously affecting people's physical and mental health. At present, the causes of arthritis disease are still unknown, and existing disease models and treatment methods are still limited, so more treatments need to be developed. Microfluidic organ chip is a cutting-edge technology to build a bionic human organ model, which can reflect the structure and function characteristics of human organs by simulating the physiological environment of tissues and cells in vitro. This paper reviews the application of microfluidic technology in the modeling and treatment of arthritis, hoping to open up a new vision for the study of arthritis.http://www.sciencedirect.com/science/article/pii/S2666138124000124MicrofluidicsArthritisOrgan on a chipDrug delivery systemDrug screening
spellingShingle Nengjie Yang
Chi Sun
Chen Dong
Yuting Huang
Yujuan Zhu
Zhifeng Gu
Emerging microfluidics for the modeling and treatment of arthritis
Engineered Regeneration
Microfluidics
Arthritis
Organ on a chip
Drug delivery system
Drug screening
title Emerging microfluidics for the modeling and treatment of arthritis
title_full Emerging microfluidics for the modeling and treatment of arthritis
title_fullStr Emerging microfluidics for the modeling and treatment of arthritis
title_full_unstemmed Emerging microfluidics for the modeling and treatment of arthritis
title_short Emerging microfluidics for the modeling and treatment of arthritis
title_sort emerging microfluidics for the modeling and treatment of arthritis
topic Microfluidics
Arthritis
Organ on a chip
Drug delivery system
Drug screening
url http://www.sciencedirect.com/science/article/pii/S2666138124000124
work_keys_str_mv AT nengjieyang emergingmicrofluidicsforthemodelingandtreatmentofarthritis
AT chisun emergingmicrofluidicsforthemodelingandtreatmentofarthritis
AT chendong emergingmicrofluidicsforthemodelingandtreatmentofarthritis
AT yutinghuang emergingmicrofluidicsforthemodelingandtreatmentofarthritis
AT yujuanzhu emergingmicrofluidicsforthemodelingandtreatmentofarthritis
AT zhifenggu emergingmicrofluidicsforthemodelingandtreatmentofarthritis