Aerobic physical training impact on adipokines in women with polycystic ovary syndrome – Effects of body fat percentage
ABSTRACT Objective: We investigated the effects of aerobic training on adipokine concentrations in women with polycystic ovary syndrome (PCOS). Subjects and methods: 120 women, including 60 with PCOS and 60 without PCOS, were divided into six groups (n = 20) based on body fat percentages of 22%-27...
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| Format: | Article |
| Language: | English |
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Brazilian Society of Endocrinology and Metabolism
2022-10-01
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| Series: | Archives of Endocrinology and Metabolism |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972022000600837&tlng=en |
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| author | Hugo Celso Dutra de Souza Stella Vieira Philbois Tábata de Paula Facioli Rui Alberto Ferriani Ada Clarice Gastaldi |
| author_facet | Hugo Celso Dutra de Souza Stella Vieira Philbois Tábata de Paula Facioli Rui Alberto Ferriani Ada Clarice Gastaldi |
| author_sort | Hugo Celso Dutra de Souza |
| collection | DOAJ |
| description | ABSTRACT Objective: We investigated the effects of aerobic training on adipokine concentrations in women with polycystic ovary syndrome (PCOS). Subjects and methods: 120 women, including 60 with PCOS and 60 without PCOS, were divided into six groups (n = 20) based on body fat percentages of 22%-27%, 28%-32%, and 33%-37%. All groups were submitted the same evaluations before and after 16 weeks of aerobic training. These included anthropometric and hemodynamic analyses, cardiopulmonary tests, and laboratory tests. Two-way analysis of variance was performed to evaluate the differences between women with and without PCOS, effect of the body fat percentage, and effect of aerobic training. Results: Body fat and PCOS were associated with high values of blood glucose, insulin, and testosterone. Body fat also reduced adiponectin levels and increased leptin, tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-6). In contrast, the PCOS increased only TNF-α and IL-6 levels. In the PCOS group, aerobic training reduced insulin, triglycerides, leptin, and IL-6 levels. It also promoted an increase in adiponectin and high-density lipoprotein levels. However, aerobic training did not alter TNF-α concentrations. Conclusion: The body fat potentiates metabolic impairments that may be harmful to women with PCOS. Aerobic training appears to promote an important beneficial effect on the metabolic regulation of adipokines, except TNF-α. |
| first_indexed | 2024-04-11T15:05:08Z |
| format | Article |
| id | doaj.art-897807cde303434cb2b2c4fd61943c69 |
| institution | Directory Open Access Journal |
| issn | 2359-4292 |
| language | English |
| last_indexed | 2024-04-11T15:05:08Z |
| publishDate | 2022-10-01 |
| publisher | Brazilian Society of Endocrinology and Metabolism |
| record_format | Article |
| series | Archives of Endocrinology and Metabolism |
| spelling | doaj.art-897807cde303434cb2b2c4fd61943c692022-12-22T04:16:49ZengBrazilian Society of Endocrinology and MetabolismArchives of Endocrinology and Metabolism2359-42922022-10-0166683784710.20945/2359-3997000000503Aerobic physical training impact on adipokines in women with polycystic ovary syndrome – Effects of body fat percentageHugo Celso Dutra de Souzahttps://orcid.org/0000-0002-0009-0005Stella Vieira Philboishttps://orcid.org/0000-0002-8276-1035Tábata de Paula Faciolihttps://orcid.org/0000-0002-8175-2989Rui Alberto Ferrianihttps://orcid.org/0000-0001-9308-8344Ada Clarice Gastaldihttps://orcid.org/0000-0001-9845-3611ABSTRACT Objective: We investigated the effects of aerobic training on adipokine concentrations in women with polycystic ovary syndrome (PCOS). Subjects and methods: 120 women, including 60 with PCOS and 60 without PCOS, were divided into six groups (n = 20) based on body fat percentages of 22%-27%, 28%-32%, and 33%-37%. All groups were submitted the same evaluations before and after 16 weeks of aerobic training. These included anthropometric and hemodynamic analyses, cardiopulmonary tests, and laboratory tests. Two-way analysis of variance was performed to evaluate the differences between women with and without PCOS, effect of the body fat percentage, and effect of aerobic training. Results: Body fat and PCOS were associated with high values of blood glucose, insulin, and testosterone. Body fat also reduced adiponectin levels and increased leptin, tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-6). In contrast, the PCOS increased only TNF-α and IL-6 levels. In the PCOS group, aerobic training reduced insulin, triglycerides, leptin, and IL-6 levels. It also promoted an increase in adiponectin and high-density lipoprotein levels. However, aerobic training did not alter TNF-α concentrations. Conclusion: The body fat potentiates metabolic impairments that may be harmful to women with PCOS. Aerobic training appears to promote an important beneficial effect on the metabolic regulation of adipokines, except TNF-α.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972022000600837&tlng=enPolycystic ovary syndromeadipokinesaerobic physical traininginflammatory markersbody fat |
| spellingShingle | Hugo Celso Dutra de Souza Stella Vieira Philbois Tábata de Paula Facioli Rui Alberto Ferriani Ada Clarice Gastaldi Aerobic physical training impact on adipokines in women with polycystic ovary syndrome – Effects of body fat percentage Archives of Endocrinology and Metabolism Polycystic ovary syndrome adipokines aerobic physical training inflammatory markers body fat |
| title | Aerobic physical training impact on adipokines in women with polycystic ovary syndrome – Effects of body fat percentage |
| title_full | Aerobic physical training impact on adipokines in women with polycystic ovary syndrome – Effects of body fat percentage |
| title_fullStr | Aerobic physical training impact on adipokines in women with polycystic ovary syndrome – Effects of body fat percentage |
| title_full_unstemmed | Aerobic physical training impact on adipokines in women with polycystic ovary syndrome – Effects of body fat percentage |
| title_short | Aerobic physical training impact on adipokines in women with polycystic ovary syndrome – Effects of body fat percentage |
| title_sort | aerobic physical training impact on adipokines in women with polycystic ovary syndrome effects of body fat percentage |
| topic | Polycystic ovary syndrome adipokines aerobic physical training inflammatory markers body fat |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972022000600837&tlng=en |
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