Muscarinic acetylcholine receptor activation prevents disinhibition-mediated LTP in the Hippocampus

Muscarinic acetylcholine receptor activation prevents disinhibition-mediated LTP in the Hippocampus

Disinhibition-mediated long-term potentiation (LTP) in the CA1 region of the hippocampus involves GABAergic synaptic plasticity at feedforward inhibitory inputs, resulting in the reduced shunting of glutamatergic excitatory currents. The GABAergic plasticity which underlies disinhibition-mediated LT...

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Bibliographic Details
Main Authors: Petri eTakkala, Melanie A Woodin
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Acetylcholine
Hippocampus
LTP
STDP
Neuromodulation
CA1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00016/full

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