IL-33 Initiates Vascular Remodelling in Hypoxic Pulmonary Hypertension by up-Regulating HIF-1α and VEGF Expression in Vascular Endothelial CellsResearch in Context

IL-33 Initiates Vascular Remodelling in Hypoxic Pulmonary Hypertension by up-Regulating HIF-1α and VEGF Expression in Vascular Endothelial CellsResearch in Context

IL-33 may play a role in the vascular remodelling of hypoxic pulmonary hypertension (PH) but the precise mechanisms are still unclear. We hypothesized that hypoxia promotes expression of IL-33 and its receptor ST2 on vascular endothelial cells, which in turn leads to dysfunction of vascular endothel...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Jie Liu, Wang Wang, Lei Wang, Shihao Chen, Bo Tian, Kewu Huang, Chris J. Corrigan, Sun Ying, Wei Wang, Chen Wang
Format: Artykuł
Język:English
Wydane: Elsevier 2018-07-01
Seria:EBioMedicine
Dostęp online:http://www.sciencedirect.com/science/article/pii/S2352396418302056

Internet

http://www.sciencedirect.com/science/article/pii/S2352396418302056

Podobne zapisy