Bioactive Metabolites Produced by Cyanobacteria for Growth Adaptation and Their Pharmacological Properties
Cyanobacteria are the most abundant oxygenic photosynthetic organisms inhabiting various ecosystems on earth. As with all other photosynthetic organisms, cyanobacteria release oxygen as a byproduct during photosynthesis. In fact, some cyanobacterial species are involved in the global nitrogen cycles...
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MDPI AG
2021-10-01
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| Online Access: | https://www.mdpi.com/2079-7737/10/10/1061 |
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| author | Pavitra Nandagopal Anthony Nyangson Steven Liong-Wai Chan Zaidah Rahmat Haryati Jamaluddin Nur Izzati Mohd Noh |
| author_facet | Pavitra Nandagopal Anthony Nyangson Steven Liong-Wai Chan Zaidah Rahmat Haryati Jamaluddin Nur Izzati Mohd Noh |
| author_sort | Pavitra Nandagopal |
| collection | DOAJ |
| description | Cyanobacteria are the most abundant oxygenic photosynthetic organisms inhabiting various ecosystems on earth. As with all other photosynthetic organisms, cyanobacteria release oxygen as a byproduct during photosynthesis. In fact, some cyanobacterial species are involved in the global nitrogen cycles by fixing atmospheric nitrogen. Environmental factors influence the dynamic, physiological characteristics, and metabolic profiles of cyanobacteria, which results in their great adaptation ability to survive in diverse ecosystems. The evolution of these primitive bacteria resulted from the unique settings of photosynthetic machineries and the production of bioactive compounds. Specifically, bioactive compounds play roles as regulators to provide protection against extrinsic factors and act as intracellular signaling molecules to promote colonization. In addition to the roles of bioactive metabolites as indole alkaloids, terpenoids, mycosporine-like amino acids, non-ribosomal peptides, polyketides, ribosomal peptides, phenolic acid, flavonoids, vitamins, and antimetabolites for cyanobacterial survival in numerous habitats, which is the focus of this review, the bioactivities of these compounds for the treatment of various diseases are also discussed. |
| first_indexed | 2024-03-10T06:43:34Z |
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| institution | Directory Open Access Journal |
| issn | 2079-7737 |
| language | English |
| last_indexed | 2024-03-10T06:43:34Z |
| publishDate | 2021-10-01 |
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| series | Biology |
| spelling | doaj.art-897e8927da1043ad85d682902e104b052023-11-22T17:29:12ZengMDPI AGBiology2079-77372021-10-011010106110.3390/biology10101061Bioactive Metabolites Produced by Cyanobacteria for Growth Adaptation and Their Pharmacological PropertiesPavitra Nandagopal0Anthony Nyangson Steven1Liong-Wai Chan2Zaidah Rahmat3Haryati Jamaluddin4Nur Izzati Mohd Noh5Department of Biosciences, Faculty of Science, Universiti Teknologi Malaysia, Skudai 81310, MalaysiaDepartment of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, Skudai 81310, MalaysiaDepartment of Biosciences, Faculty of Science, Universiti Teknologi Malaysia, Skudai 81310, MalaysiaDepartment of Biosciences, Faculty of Science, Universiti Teknologi Malaysia, Skudai 81310, MalaysiaDepartment of Biosciences, Faculty of Science, Universiti Teknologi Malaysia, Skudai 81310, MalaysiaDepartment of Biosciences, Faculty of Science, Universiti Teknologi Malaysia, Skudai 81310, MalaysiaCyanobacteria are the most abundant oxygenic photosynthetic organisms inhabiting various ecosystems on earth. As with all other photosynthetic organisms, cyanobacteria release oxygen as a byproduct during photosynthesis. In fact, some cyanobacterial species are involved in the global nitrogen cycles by fixing atmospheric nitrogen. Environmental factors influence the dynamic, physiological characteristics, and metabolic profiles of cyanobacteria, which results in their great adaptation ability to survive in diverse ecosystems. The evolution of these primitive bacteria resulted from the unique settings of photosynthetic machineries and the production of bioactive compounds. Specifically, bioactive compounds play roles as regulators to provide protection against extrinsic factors and act as intracellular signaling molecules to promote colonization. In addition to the roles of bioactive metabolites as indole alkaloids, terpenoids, mycosporine-like amino acids, non-ribosomal peptides, polyketides, ribosomal peptides, phenolic acid, flavonoids, vitamins, and antimetabolites for cyanobacterial survival in numerous habitats, which is the focus of this review, the bioactivities of these compounds for the treatment of various diseases are also discussed.https://www.mdpi.com/2079-7737/10/10/1061cyanobacteriahabitatadaptation strategiesbioactive metabolites |
| spellingShingle | Pavitra Nandagopal Anthony Nyangson Steven Liong-Wai Chan Zaidah Rahmat Haryati Jamaluddin Nur Izzati Mohd Noh Bioactive Metabolites Produced by Cyanobacteria for Growth Adaptation and Their Pharmacological Properties Biology cyanobacteria habitat adaptation strategies bioactive metabolites |
| title | Bioactive Metabolites Produced by Cyanobacteria for Growth Adaptation and Their Pharmacological Properties |
| title_full | Bioactive Metabolites Produced by Cyanobacteria for Growth Adaptation and Their Pharmacological Properties |
| title_fullStr | Bioactive Metabolites Produced by Cyanobacteria for Growth Adaptation and Their Pharmacological Properties |
| title_full_unstemmed | Bioactive Metabolites Produced by Cyanobacteria for Growth Adaptation and Their Pharmacological Properties |
| title_short | Bioactive Metabolites Produced by Cyanobacteria for Growth Adaptation and Their Pharmacological Properties |
| title_sort | bioactive metabolites produced by cyanobacteria for growth adaptation and their pharmacological properties |
| topic | cyanobacteria habitat adaptation strategies bioactive metabolites |
| url | https://www.mdpi.com/2079-7737/10/10/1061 |
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