Reduction of sevoflurane and fentanyl consumption through dexmedetomidine use as a part of general anesthesia in oncogynecological surgery (a prospective blind randomized study)

The objective: to compare hemodynamic parameters, expiratory concentration of sevoflurane, fentanyl consumption during the surgery, the intensity of the pain syndrome during general combined anesthesia with and without dexmedetomidine.Subjects and methods: a prospective, blind, randomized study was...

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Main Authors: K. A. Tsygаnkov, R. E. Lаkhin, D. A. Аveryanov, A. V. Schegolev, A. A. Аndreenko, A. D. Khаlikov
Format: Article
Language:Russian
Published: New Terra Publishing House 2019-11-01
Series:Вестник анестезиологии и реаниматологии
Subjects:
Online Access:https://www.vair-journal.com/jour/article/view/374
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author K. A. Tsygаnkov
R. E. Lаkhin
D. A. Аveryanov
A. V. Schegolev
A. A. Аndreenko
A. D. Khаlikov
author_facet K. A. Tsygаnkov
R. E. Lаkhin
D. A. Аveryanov
A. V. Schegolev
A. A. Аndreenko
A. D. Khаlikov
author_sort K. A. Tsygаnkov
collection DOAJ
description The objective: to compare hemodynamic parameters, expiratory concentration of sevoflurane, fentanyl consumption during the surgery, the intensity of the pain syndrome during general combined anesthesia with and without dexmedetomidine.Subjects and methods: a prospective, blind, randomized study was performed in patients with oncogynecological disorders divided into two groups, where dexmedetomidine was used and not.Results. In the studied groups, changes in hemodynamics, expiratory concentration of sevoflurane, and fentanyl consumption were observed. There was no difference in the pain intensity between the groups.Conclusions. The expiratory concentration of sevoflurane, as well as the consumption of fentanyl, were lower in the group where dexmedetomidine was used. The intensity of the pain syndrome did not differ between two groups.
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spelling doaj.art-8981d292337040cfb3fd5f5f61475b732025-03-02T10:44:32ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532019-11-01165495510.21292/2078-5658-2019-16-5-49-55345Reduction of sevoflurane and fentanyl consumption through dexmedetomidine use as a part of general anesthesia in oncogynecological surgery (a prospective blind randomized study)K. A. Tsygаnkov0R. E. Lаkhin1D. A. Аveryanov2A. V. Schegolev3A. A. Аndreenko4A. D. Khаlikov5S.M. Kirov Military Medical AcademyS.M. Kirov Military Medical AcademyS.M. Kirov Military Medical AcademyS.M. Kirov Military Medical AcademyS.M. Kirov Military Medical AcademyCity Clinical Oncology DispensaryThe objective: to compare hemodynamic parameters, expiratory concentration of sevoflurane, fentanyl consumption during the surgery, the intensity of the pain syndrome during general combined anesthesia with and without dexmedetomidine.Subjects and methods: a prospective, blind, randomized study was performed in patients with oncogynecological disorders divided into two groups, where dexmedetomidine was used and not.Results. In the studied groups, changes in hemodynamics, expiratory concentration of sevoflurane, and fentanyl consumption were observed. There was no difference in the pain intensity between the groups.Conclusions. The expiratory concentration of sevoflurane, as well as the consumption of fentanyl, were lower in the group where dexmedetomidine was used. The intensity of the pain syndrome did not differ between two groups.https://www.vair-journal.com/jour/article/view/374general combined anesthesiadexmedetomidineα2-adrenoceptor agonistsanesthesia in cancer patients
spellingShingle K. A. Tsygаnkov
R. E. Lаkhin
D. A. Аveryanov
A. V. Schegolev
A. A. Аndreenko
A. D. Khаlikov
Reduction of sevoflurane and fentanyl consumption through dexmedetomidine use as a part of general anesthesia in oncogynecological surgery (a prospective blind randomized study)
Вестник анестезиологии и реаниматологии
general combined anesthesia
dexmedetomidine
α2-adrenoceptor agonists
anesthesia in cancer patients
title Reduction of sevoflurane and fentanyl consumption through dexmedetomidine use as a part of general anesthesia in oncogynecological surgery (a prospective blind randomized study)
title_full Reduction of sevoflurane and fentanyl consumption through dexmedetomidine use as a part of general anesthesia in oncogynecological surgery (a prospective blind randomized study)
title_fullStr Reduction of sevoflurane and fentanyl consumption through dexmedetomidine use as a part of general anesthesia in oncogynecological surgery (a prospective blind randomized study)
title_full_unstemmed Reduction of sevoflurane and fentanyl consumption through dexmedetomidine use as a part of general anesthesia in oncogynecological surgery (a prospective blind randomized study)
title_short Reduction of sevoflurane and fentanyl consumption through dexmedetomidine use as a part of general anesthesia in oncogynecological surgery (a prospective blind randomized study)
title_sort reduction of sevoflurane and fentanyl consumption through dexmedetomidine use as a part of general anesthesia in oncogynecological surgery a prospective blind randomized study
topic general combined anesthesia
dexmedetomidine
α2-adrenoceptor agonists
anesthesia in cancer patients
url https://www.vair-journal.com/jour/article/view/374
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