Therapeutic Effect of Extracellular Vesicles Derived from HIF Prolyl Hydroxylase Domain Enzyme Inhibitor-Treated Cells on Renal Ischemia/Reperfusion Injury

Therapeutic Effect of Extracellular Vesicles Derived from HIF Prolyl Hydroxylase Domain Enzyme Inhibitor-Treated Cells on Renal Ischemia/Reperfusion Injury

Introduction: Acute kidney injury (AKI) is a major public health problem worldwide. However, there is no definitive therapies to treat established AKI. In this study, we used FG-4592 to induce hypoxia inducible factor (HIF) expression in cells and then explored whether the extracellular vesicles (EV...

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Bibliographic Details
Main Authors: Zhao-Ying Ding, Tao-Tao Tang, Zuo-Lin Li, Jing-Yuan Cao, Lin-Li Lv, Yi Wen, Bin Wang, Bi-Cheng Liu
Format: Article
Language:English
Published: Karger Publishers 2022-03-01
Series:Kidney Diseases
Subjects:
acute kidney injury
exosome
hif-phi
Online Access:https://www.karger.com/Article/FullText/522584

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